TBTU [Coupling Reagent for Peptide] TCI B1658

Chemical Identity

Other names: TBTU
CAS No.: 125700-67-6
PubChem: CID 2733207·SID 87564559
Formula: C11H16BF4N5O
Molecular weight: 321.08 g/mol
Purity: >98.0%(HPLC)
Reference databases: ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: [benzotriazol-1-yloxy(dimethylamino)methylidene]-dimethylazanium tetrafluoroborate
SMILES: [B-](F)(F)(F)F.CN(C)C(=[N+](C)C)ON1C2=CC=CC=C2N=N1
InChIKey: JKEKMBGUVUKMQB-UHFFFAOYSA-N

Rp 1.563.450,00

~~Rp 1.108.800,00~~ Rp 1.563.450,00

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TBTU, or N-tert-Butyloxycarbonyl-3-(2-piperidinyl)propionamide, is a coupling reagent widely used in peptide synthesis. As a key component in chemical biology, it plays a crucial role in the formation of peptide chains by facilitating the covalent bonding between amino acids. This reagent is essential for researchers working in peptide chemistry, enabling the construction of complex molecular structures with high precision. Its ability to form stable and selective peptide bonds makes it a reliable tool in various biochemical applications.

TBTU is valued for its chemical stability and high reactivity, which allow it to function effectively under specific reaction conditions. Its strong binding capacity ensures efficient coupling reactions without compromising the integrity of the final molecular structure. These properties make it a preferred choice for scientists aiming to accelerate peptide synthesis while maintaining the accuracy and quality of their results. The reagent's reliability and efficiency have solidified its position as a standard in peptide chemistry research.

In Indonesian laboratories, TBTU is extensively used in biomedical, pharmacological, and biotechnological research. It supports the development of new drugs, the study of molecular interactions, and the production of peptide-based compounds. Its widespread application across various research institutions and universities highlights its importance in advancing scientific knowledge and innovation in the field of peptide chemistry.

TCI brochures (PDF)

Condensing Agents 2025-11-18 · p. 7
Boron Compounds 2025-10-07 · p. 24
Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 37
Reagents for Biological Research 2025-03-11 · p. 59

Related TCI products

Peptide Synthesis: TBTU is ideal for peptide synthesis due to its ability to form stable and selective peptide bonds, enabling the construction of complex molecular structures with high efficiency.
Drug Development: This reagent supports the creation of new pharmaceutical compounds by facilitating the synthesis of peptide-based drugs, which are essential in modern medicine.
Molecular Interaction Studies: TBTU is used to study molecular interactions in biomedicine, allowing researchers to analyze how peptides interact with proteins and other biomolecules.
Biotechnology Research: It plays a key role in biotechnology by enabling the production of bioactive peptides and proteins, which are vital for various industrial and therapeutic applications.
Structural Analysis: TBTU aids in structural analysis of peptides and proteins, contributing to the understanding of their functional properties and biological roles.

Brand	TCI
CAS number	125700-67-6
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes	Available in various quantities as per standard laboratory requirements
Physical form	Solid powder
Storage	Store in a cool, dry place away from moisture and direct sunlight

TBTU should be stored in a cool, dry environment to maintain its chemical stability and reactivity. It is recommended to keep it in a sealed container to prevent exposure to moisture and air, which could affect its performance. Due to its chemical nature, it should be handled with care in a well-ventilated laboratory setting. Avoid direct contact with skin and eyes, and use appropriate personal protective equipment such as gloves and safety goggles. Proper storage and handling ensure the reagent remains effective and safe for use in peptide synthesis and related research applications.

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