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TCI C0119 1,1'-Carbonyldiimidazole (CAS 530-62-1) is a widely used carbonyl activating agent for peptide and general amide bond formation. It converts carboxylic acids into reactive acyl imidazolides that readily couple with amines, alcohols, and other nucleophiles under mild conditions. Its by-products, imidazole and carbon dioxide, are typically easy to remove, simplifying downstream purification. Supplied by TCI in 5 g, 25 g, and 250 g packs, the reagent is highly moisture sensitive and should be handled under dry, inert conditions.
TCI brochures (PDF)
- Condensing Agents 2025-11-18 · p. 6
- Bioconjugation Reagents 2026-07-07 · p. 12
- Reagents for Glyco Chemistry & Biology 5th Edition · p. 133
- Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 39
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Product Categories
- Chemical BiologyPeptide ChemistryPeptide Coupling Agents
- Chemical BiologyGlycoscienceReagents for Oligosaccharide Synthesis [Glycoscience]
- Chemical BiologyBioconjugationZero-length Crosslinkers
- Synthetic ReagentsC-C Bond Formation [Synthetic Reagents]Carbon Monoxide Surrogate Reagents [C-C Bond Formation]
- Synthetic ReagentsCoupling [Synthetic Reagents]Carbonyldiimidazole Derivatives [Coupling Reagents]
- Pharmaceutical Development and Drug Discovery Research ReagentsPeptide ChemistryPeptide Coupling Agents
- GlycoscienceReagents for Oligosaccharide Synthesis [Glycoscience]
- Biochemicals and ReagentsBioconjugationZero-length Crosslinkers
- Pharmaceutical Development and Drug Discovery ResearchBioconjugationZero-length Crosslinkers
- Pharmaceutical Development and Drug Discovery ResearchPeptide ChemistryPeptide Coupling Agents
Produk Terkait
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