TCI C0793 CMC (CAS 2491-17-0) is a water-soluble carbodiimide reagent developed for peptide synthesis and bioconjugation. Its quaternary ammonium moiety allows carboxyl activation and amide bond formation to proceed in aqueous media, which is valuable when working with sensitive biomolecules. Typical uses include peptide coupling, enzyme and biomolecule immobilisation, hydrogel crosslinking, and carbodiimide-based chemical probing of nucleic acids. Supplied by TCI in 5 g and 25 g packs, the salt is hygroscopic and should be kept cold, dry, and tightly closed.
TCI brochures (PDF)
- RNA Structure Analysis Reagents 2026-08-20 · p. 2
- Condensing Agents 2025-11-18 · p. 6
- Bioconjugation Reagents 2026-07-07 · p. 12
- Quaternary Ammonium Salts 2025-11-10 · p. 10
- Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 39
Related TCI products
- TCI D1601 25952-53-8 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride [Coupling Agent for Peptides Synthesis]
- TCI C0119 530-62-1 1,1'-Carbonyldiimidazole [Coupling Agent for Peptides Synthesis]
- TCI D4029 1892-57-5 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide
- TCI D0254 693-13-0 N,N'-Diisopropylcarbodiimide
- TCI H0528 21715-90-2 N-Hydroxy-5-norbornene-2,3-dicarboximide [for Peptide Synthesis]
- TCI C2363 953-91-3 Cyclohexyl p-Toluenesulfonate
From the TCI brochure
- Nucleobase-specific probing of RNA to detect higher-order structures
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Data from the TCI brochure
| Main modification positions | Guanine N1, Uracil N1 (Formation of CMCT Adduct) |
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Source: TCI brochure LL098 (2026-08-20)
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