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TCI

CAS 72040-64-3

6-Biotinamidohexanoic Acid TCI B2433

6-Biotinamidohexanoic Acid TCI B2433

Chemical Identity

CAS No.
72040-64-3
PubChem
CID 446905·SID 253659652
Formula
C16H27N3O4S
Molecular weight
357.5 g/mol
Purity
>97.0%(HPLC)(T)
Reference databases
ChemSpider
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]hexanoic acid
SMILES
C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCCCCC(=O)O)NC(=O)N2
InChIKey
CMUGHZFPFWNUQT-HUBLWGQQSA-N
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6-Biotinamidohexanoic Acid (BHA) is a chemical compound widely used in bioconjugation applications within laboratory settings. It serves as a crucial linker between biotin and target molecules, enabling the specific attachment of biotin to various substances such as proteins, nucleic acids, and lipids. This compound plays a vital role in biochemical and molecular biology research by facilitating the creation of highly specific and efficient biotin-avidin systems. Its ability to form stable conjugates makes it an essential tool for researchers working on complex molecular interactions.

The properties of BHA that make it a preferred choice include its stable chemical structure and favorable reactivity, which allow for selective and effective chemical reactions. Additionally, BHA exhibits amphiprotic characteristics, enabling it to interact with different types of molecules under varying pH conditions. This versatility makes it suitable for a wide range of experimental setups. Its chemical stability and reactivity ensure consistent results, making it a reliable reagent for laboratory applications.

In Indonesian laboratories, BHA is extensively used in biochemical, biomedical, and molecular biology research. It is particularly relevant for studies requiring the specific binding of biotin to target molecules. Applications include the development of biochemical sensors, diagnostic testing, and biological therapy research. Its adaptability and effectiveness make it a valuable component in many scientific investigations.

  • Bioconjugation Research - BHA is ideal for creating biotin-ligand conjugates due to its stable structure and reactive groups, enabling efficient and selective molecular binding.
  • Diagnostic Testing - BHA supports the development of sensitive assays by allowing precise attachment of biotin to biomarkers, enhancing detection accuracy.
  • Molecular Biology Studies - It is used in labeling proteins and nucleic acids for tracking and analysis, offering high specificity and reliability in experimental results.
  • Sensor Development - BHA facilitates the creation of biochemical sensors by enabling the attachment of biotin to sensor surfaces, improving sensitivity and response time.
  • Therapeutic Research - It aids in the design of targeted drug delivery systems by conjugating biotin to therapeutic agents, enhancing their specificity and efficacy.

Brand TCI
CAS number 72040-64-3
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Bioconjugation
Pack sizes Available in various quantities as per standard laboratory supply
Physical form Solid powder
Storage Store in a cool, dry place away from light and moisture

BHA should be stored in a cool, dry place, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Avoid contact with incompatible substances and ensure proper ventilation when working with the compound. Regular monitoring of storage conditions is advised to maintain the integrity of the material for optimal performance in experimental applications.

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