N-Succinimidyl 9-(Biotinamido)-4,7-dioxanonanoate TCI S0955

Chemical Identity

Other names: Biotin-PEG2-NHS
CAS No.: 596820-83-6
PubChem: CID 91757819·SID 354333526
Formula: C21H32N4O8S
Molecular weight: 500.6 g/mol
Purity: >90.0%(qNMR)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]propanoate
SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCNC(=O)CCCC[C@H]2[C@@H]3[C@H](CS2)NC(=O)N3
InChIKey: UCJSJBIJPAZUGU-AVYPCKFXSA-N

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N-Succinimidyl 9-(Biotinamido)-4,7-dioxanonanoate is a chemical reagent widely used in bioconjugation applications to link biological molecules with biotin. This compound plays a crucial role in laboratories where molecular interactions need to be precisely controlled. It is commonly employed in biomedical and chemical biology research to modify proteins, peptides, or nucleic acids for specific binding with avidin or streptavidin. Its utility lies in its ability to facilitate targeted molecular modifications, making it an essential tool for advanced research.

The reagent's reactive and specific nature allows it to form stable covalent bonds with amino groups on proteins or other biomolecules. Its chemical structure ensures strong and durable conjugates, which are vital for applications requiring long-term stability and reliability. These properties make it a preferred choice for researchers aiming to achieve high precision in molecular modifications. The compound's effectiveness in creating specific and reliable connections is a key factor in its widespread use across various scientific disciplines.

In Indonesian laboratories, this reagent is extensively used in biomedical, pharmacological, and biotechnological research. It supports studies focused on drug development, molecular diagnostics, and biological modification. Its availability ensures that local research institutions can conduct advanced experiments requiring precise molecular interactions. The compound's role in enhancing research capabilities makes it a valuable asset for scientific innovation in Indonesia.

TCI brochures (PDF)

Pre-Weighed Biotinylation Reagents 2025-03-25 · p. 2
Europium Fluorescent Labeling Reagent and Labeled Probes 2025-01-30 · p. 4
Streptavidins and Related Reagents 2025-02-28 · p. 3
Biotinylation Reagents and Avidins 2025-06-26 · p. 1
Protein and Biological Sample Preparation Reagents 2026-09-10 · p. 16
Bioconjugation Reagents 2026-07-07 · p. 2

Related TCI products

Bioconjugation Research: This reagent is ideal for creating stable biotinylated molecules, enabling specific binding with avidin or streptavidin for use in assays and labeling techniques.
Protein Modification: It facilitates the covalent attachment of biotin to proteins, enhancing their detectability and functionality in various biochemical applications.
Peptide Conjugation: The compound allows for the precise modification of peptides, making them suitable for use in diagnostic tools and therapeutic applications.
Nucleic Acid Labeling: It enables the biotinylation of nucleic acids, supporting molecular biology experiments such as hybridization and detection methods.
Drug Development: The reagent supports the creation of biotinylated drug candidates, aiding in the study of molecular interactions and therapeutic efficacy.

Brand	TCI
CAS number	596820-83-6
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Bioconjugation
Pack sizes	Available in various quantities as per supplier specifications
Physical form	Solid or powder, depending on the batch
Storage	Store in a cool, dry place away from light and moisture

This reagent should be stored in a cool, dry environment, away from direct light and moisture to maintain its stability and effectiveness. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its reactive nature, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. Proper ventilation is essential when working with this compound to minimize inhalation risks. It should not be disposed of in drains or landfills without following local regulations for chemical waste. Always follow standard laboratory safety protocols to ensure safe handling and storage.

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