[1,1'-Biphenyl]-2-carboxaldehyde (CAS 1203-68-5) is a versatile non-heterocyclic building block that combines a rigid biaryl framework with a highly reactive ortho-positioned aldehyde group. This arrangement makes it a convenient precursor for intramolecular cyclisations toward fluorenone and phenanthridine-type scaffolds, as well as for classical carbonyl transformations such as Wittig olefination and reductive amination. Supplied by TCI under product code B6334, it is offered in 5 g and 25 g packs to suit both method optimisation and repeated synthetic campaigns. Store the material in a cool, dry, light-protected place and always consult the manufacturer's Safety Data Sheet before handling.
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- Alkhudari (2021). Condensation Reactions of Methyl Derivatives of Quinoxaline-1,4-Dioxide with 4,4'-Biphenyl Carboxaldehyde. Asian Journal of Chemical Sciences doi:10.9734/ajocs/2021/v10i119083
- Iwan et al. (2010). Synthesis, characterization and mesomorphic properties of new unsymmetrical azomethine-type liquid crystals derived from 4-biphenyl carboxaldehyde. Journal of Molecular Liquids doi:10.1016/j.molliq.2009.10.015
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