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Description
TCI B6456 1-Bromo-2-pentyne (CAS 16400-32-1) is a reactive propargylic bromide supplied as a non-heterocyclic building block. It readily alkylates carbon, nitrogen, oxygen, and sulfur nucleophiles, installing a pentynyl fragment that can be elaborated further through click chemistry or metal-catalyzed coupling. The reagent is flammable and lachrymatory, so all transfers should be performed inside a fume hood with suitable protective equipment. Store it tightly closed in a cool, dark, well-ventilated area away from ignition sources and oxidizing agents.
