TCI 5-Chloro-1-pentyne (CAS 14267-92-6) is a bifunctional C5 building block bearing a terminal alkyne at one end and a primary alkyl chloride at the other. This complementary reactivity allows chemists to couple one terminus while reserving the other for a later transformation, making it a convenient flexible linker. It is widely used in click chemistry, Sonogashira couplings, and nucleophilic alkylation to introduce a pentynyl chain. AMI Scientific supplies it in 5 mL and 25 mL laboratory packs; please refer to the manufacturer's Safety Data Sheet for full handling and storage guidance.
TCI brochures (PDF)
- Click Chemistry 2026-09-08 · p. 11
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