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Description
TCI C1493 6-Chloro-1-hexyne (CAS 10297-06-0) is a bifunctional building block carrying a terminal alkyne and a primary alkyl chloride separated by a six-carbon chain. The alkyne enables copper-catalysed azide–alkyne cycloaddition, Sonogashira coupling, and acetylide chemistry, while the chloride undergoes straightforward nucleophilic substitution. This orthogonal reactivity makes it a convenient linker for bioconjugation, probe synthesis, and surface functionalisation. Supplied in 5 mL and 25 mL packs; it is a volatile flammable liquid, so handle in a fume hood per the Safety Data Sheet.
