3-(5-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione TCI B6528

Chemical Identity

Other names: Lenalidomide-5-Br · 3-(5-Bromo-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2,6-piperidinedione
CAS No.: 1010100-26-1
PubChem: CID 69049011
Formula: C13H11BrN2O3
Molecular weight: 323.15 g/mol
Purity: >90.0%(HPLC)(qNMR)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 3-(6-bromo-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
SMILES: C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC(=C3)Br
InChIKey: CMRQAKJTXKOGSF-UHFFFAOYSA-N
MDL: MDL32263142

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Berat 100mg 1g

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TCI B6528, 3-(5-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione (CAS 1010100-26-1), provides an isoindolinone–glutarimide core that functions as a cereblon-binding motif in targeted protein degradation research. The bromine at the 5-position acts as a convenient handle for attaching linkers through palladium-catalysed cross-coupling chemistry. It allows researchers to compare isoindolinone-based ligands with phthalimide-based analogues within a single degrader series. Supplied by AMI Scientific in original TCI packaging in 100 mg and 1 g sizes, this product is for research use only.