5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione TCI B6550

Chemical Identity

Other names: 5-Bromo-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione · 4-Bromo-N-(2,6-dioxo-3-piperidyl)phthalimide
CAS No.: 26166-92-7
PubChem: CID 44435680
Formula: C13H9BrN2O4
Molecular weight: 337.13 g/mol
Purity: >95.0%(HPLC)(T)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)Br
InChIKey: MWMSBQXTHIEBNT-UHFFFAOYSA-N
MDL: MDL30188073

Rp 1.881.600,00

~~Rp 1.331.400,00~~ Rp 1.881.600,00

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5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (CAS 26166-92-7) is a brominated phthalimide–glutarimide derivative used as a cereblon-binding ligand in targeted protein degradation research. Its aryl bromide handle is well suited to palladium-catalysed cross-couplings such as Suzuki and Buchwald–Hartwig reactions, allowing convenient linker attachment during PROTAC assembly. Because of the pharmacological sensitivity of the glutarimide class, the compound should be weighed with full personal protective equipment in a fume hood and stored cool, dry, and protected from light. AMI Scientific supplies it in 1 g and 5 g pack sizes strictly for laboratory research use.