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TCI

CAS 835616-61-0

2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione TCI D5969

2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione TCI D5969
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Description

2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione is a chemical compound used in pharmaceutical research and drug development. It belongs to the category of Proteolysis Targeting Chimera (PROTAC) research reagents, which is a cutting-edge approach in modern drug discovery. This compound functions as a modulator that facilitates the interaction between target proteins and E3 ubiquitin ligases, enabling the specific degradation of proteins involved in various diseases. Its role in the laboratory is critical for understanding protein function and developing targeted therapies.

The compound is valued for its stable chemical properties and controlled reactivity, making it suitable for use in a wide range of experimental conditions. Its complex structure allows for specific interactions with target proteins, enhancing its effectiveness in research applications. The solid form of the compound ensures ease of handling and storage, while its chemical stability supports consistent results in laboratory experiments. These characteristics make it a preferred choice for researchers working in pharmaceutical and biochemical fields.

In Indonesian laboratories, this compound is commonly used in applied research for the development of new drugs, particularly in oncology and metabolic disease studies. Researchers across various institutions utilize it to study protein mechanisms and develop therapies that target specific disease pathways. Its relevance in both basic and applied research underscores its importance in the scientific community.

Laboratory Applications

  • Used in PROTAC-based drug discovery to enable targeted protein degradation through E3 ligase interactions.
  • Applied in biochemical research to study protein-protein interactions and molecular mechanisms of disease.
  • Utilized in pharmaceutical development for the synthesis of novel therapeutic agents with high specificity.
  • Employed in oncology research to investigate the degradation of proteins involved in cancer progression.
  • Integrated into metabolic disease studies to explore the role of specific proteins in metabolic pathways.

Specifications

  • Brand: TCI
  • CAS number: 835616-61-0
  • Category: Chemistry > Pharmaceutical Development and Drug Discovery Research Reagents > Proteolysis Targeting Chimera Research Reagents
  • Pack sizes: Available in various quantities as per standard laboratory reagent packaging
  • Physical form: Solid
  • Storage note: Store in a cool, dry place away from direct light

Handling and Storage

This compound should be stored in a cool, dry environment, away from direct sunlight and sources of heat. It is recommended to use airtight containers to prevent moisture absorption and contamination. Due to its chemical stability, it does not require refrigeration but should be protected from environmental factors that may affect its integrity. In a laboratory setting, it is important to handle the compound with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safe handling. Proper labeling of containers is essential to avoid confusion and ensure safe storage practices. General laboratory precautions include maintaining a clean workspace and following standard safety protocols when working with chemical reagents.

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