TCI
2-(2,6-Dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione TCI D6134
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Description
2-(2,6-Dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione is a chemical compound widely utilized in pharmaceutical research and development. This reagent plays a crucial role in laboratory settings where scientists investigate molecular interactions and the development of compounds that can be selectively degraded by enzymes in the body. Its complex structure makes it an essential tool for studying proteolysis targeting chimera (PTC), a method used to design drugs that are specifically degraded by the body’s own mechanisms. This compound is particularly valuable in drug discovery due to its potential to interact with biological targets such as proteins and enzymes.
The compound is chemically stable and soluble in specific organic solvents, which facilitates its use in various chemical and pharmacological experiments. These properties make it a preferred choice for researchers aiming to develop highly specific and stable compounds. Its solubility and stability ensure that it remains effective throughout experimental procedures, reducing the risk of degradation or loss of activity. Additionally, the compound’s molecular structure allows for precise interactions with biological systems, making it a versatile reagent in pharmaceutical research.
In Indonesian laboratories, this compound is commonly used in pharmacological studies, drug development, and molecular interaction research. Its role in PTC research has made it a key component in the development of targeted therapies. Scientists in Indonesia rely on this compound to advance their understanding of molecular mechanisms and to create more effective and safer therapeutic agents.
Laboratory Applications
- Pharmaceutical development and drug discovery research benefits from this compound's ability to interact with biological targets, enabling the design of more effective therapeutic agents.
- Proteolysis targeting chimera (PTC) research utilizes this reagent to study compounds that can be selectively degraded by the body’s enzymes, improving drug safety and efficacy.
- Molecular interaction studies leverage the compound’s complex structure to investigate how it binds to proteins and enzymes, contributing to the understanding of biological processes.
- Chemical synthesis experiments use the compound as a building block due to its stability and solubility in organic solvents, facilitating the creation of new chemical entities.
- Pharmacological research incorporates this reagent to test the effects of compounds on biological systems, supporting the development of novel treatments for various diseases.
Specifications
- Brand: TCI
- CAS number: 5054-59-1
- Category: Chemistry > Pharmaceutical Development and Drug Discovery Research Reagents > Proteolysis Targeting Chimera Research Reagents
- Pack sizes: As per manufacturer specifications
- Physical form: Solid or crystalline (as per product description)
- Storage note: Store in a cool, dry place away from light
Handling and Storage
This compound should be stored in a cool, dry place away from direct light to maintain its chemical stability. It is recommended to use airtight containers to prevent moisture absorption and contamination. Due to its organic nature, it should be handled in a well-ventilated area to minimize exposure. Laboratory personnel should wear appropriate personal protective equipment, such as gloves and safety goggles, when handling the compound. Proper disposal procedures must be followed to ensure environmental and safety compliance. The compound is not hazardous under normal storage conditions, but care should be taken to avoid contact with skin or inhalation of vapors.
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