![[1,1'-Biphenyl]-2-carbonyl Chloride (CAS 14002-52-9) - TCI B6543 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510B6543.jpg?v=1767093866&width=1946)
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[1,1'-Biphenyl]-2-carbonyl chloride (CAS 14002-52-9) is a highly reactive acyl chloride bearing the acyl group ortho to the biphenyl linkage. It reacts readily with amines and alcohols to give biphenyl-2-carboxamides and esters, and can also acylate aromatic rings under Friedel–Crafts conditions. Because acid chlorides hydrolyse on contact with moisture and release corrosive HCl, the reagent must be handled in a fume hood using dry glassware, anhydrous solvents, and preferably an inert atmosphere. AMI Scientific offers 200 mg and 1 g pack sizes for synthetic and medicinal chemistry laboratories.
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