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CAS 14002-52-9

[1,1'-Biphenyl]-2-carbonyl Chloride TCI B6543

[1,1'-Biphenyl]-2-carbonyl Chloride TCI B6543

Chemical Identity

Other names
2-Biphenylcarbonyl Chloride
CAS No.
14002-52-9
PubChem
CID 12563768
Formula
C13H9ClO
Molecular weight
216.66 g/mol
Purity
>98.0%(GC)(T)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
2-phenylbenzoyl chloride
SMILES
C1=CC=C(C=C1)C2=CC=CC=C2C(=O)Cl
InChIKey
MPJOJCZVGBOVOV-UHFFFAOYSA-N
MDL
MDL09745399
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[1,1'-Biphenyl]-2-carbonyl chloride (CAS 14002-52-9) is a highly reactive acyl chloride bearing the acyl group ortho to the biphenyl linkage. It reacts readily with amines and alcohols to give biphenyl-2-carboxamides and esters, and can also acylate aromatic rings under Friedel–Crafts conditions. Because acid chlorides hydrolyse on contact with moisture and release corrosive HCl, the reagent must be handled in a fume hood using dry glassware, anhydrous solvents, and preferably an inert atmosphere. AMI Scientific offers 200 mg and 1 g pack sizes for synthetic and medicinal chemistry laboratories.

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