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Description
TCI B6672, 2-Bromo-1-(4-ethylphenyl)ethan-1-one (CAS 2632-14-6), is a phenacyl bromide bearing a para-ethyl substituent on the aromatic ring. The bromine atom alpha to the carbonyl makes it highly reactive toward nitrogen, sulfur, and oxygen nucleophiles, and it is widely used in Hantzsch thiazole synthesis. Medicinal chemists value it as a convenient way to introduce a functionalized aryl ketone fragment into compound libraries. AMI Scientific supplies this TCI building block in 1 g and 5 g pack sizes; note that phenacyl bromides are lachrymatory and should always be handled in a fume hood.
