Flunarizine Dihydrochloride TCI B6727

Chemical Identity

Other names: (E)-1-[Bis(4-fluorophenyl)methyl]-4-cinnamylpiperazine Dihydrochloride
CAS No.: 30484-77-6
PubChem: CID 5282407
Formula: C26H26F2N2.2HCl
Molecular weight: 477.42 g/mol
Purity: >98.0%(HPLC)(T)
Storage: 0-10°C
Reference databases: ChEBI·ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;dihydrochloride
SMILES: C1CN(CCN1CC=CC2=CC=CC=C2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl.Cl
InChIKey: RXKMOPXNWTYEHI-RDRKJGRWSA-N
MDL: MDL00058198

Rp 2.359.350,00

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TCI B6727 Flunarizine Dihydrochloride (CAS 30484-77-6) is a diphenylpiperazine-class calcium channel blocker supplied as a pharmaceutical research reagent for experimental use. Researchers apply it as a pharmacological tool to probe calcium entry and related signalling pathways in cell and tissue models. The dihydrochloride salt form simplifies handling and stock solution preparation compared with the free base. AMI Scientific supplies the 25 g size, and the material is intended strictly for laboratory research rather than human, clinical, or therapeutic use.

TCI brochures (PDF)

Immune System, Inflammation, Allergy Research Reagents 2025-05-26 · p. 4
Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 35

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AMJ et al. (2017). Flunarizine Dihydrochloride Nanoemulsion for Migraine Nasal Drug Delivery: Fabrication, Characterization and In Vitro Study. Drug Delivery Letters doi:10.2174/2210303106666160930113725
Yelli et al. (2022). Development and validation of dissolution testing of Flunarizine dihydrochloride in tablet dosage form. Pharmacy Education doi:10.46542/pe.2022.222.132137
Upadhyay et al. (2018). Molecular recognition of flunarizine dihydrochloride and β-cyclodextrin inclusion complex by NMR and computational approaches. Chemistry Central Journal doi:10.1186/s13065-018-0395-4

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.