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Description
TCI C0266 1-Chloropropane (CAS 540-54-5) is a primary alkyl halide widely used as a propylating agent in nucleophilic substitution chemistry. It also serves as a precursor to n-propyl Grignard reagents and as a teaching example for SN1 and SN2 mechanism studies. The compound is a highly flammable, volatile liquid and must be handled in a fume hood away from ignition sources. It is available in 25 mL and 500 mL packs for both small-scale trials and routine synthesis.
Scientific References
Saheb (2013). Theoretic studies on the kinetics and mechanism of multi-channel gas-phase unimolecular reactions of 1-chloropropane and 2-chloropropane. Structural Chemistrydoi:10.1007/s11224-013-0240-2
Ermacora et al. (2014). Influence of oil composition on the formation of fatty acid esters of 2-chloropropane-1,3-diol (2-MCPD) and 3-chloropropane-1,2-diol (3-MCPD) under conditions simulating oil refining. Food Chemistrydoi:10.1016/j.foodchem.2014.03.130
Gronert (1993). Theoretical studies of elimination reactions. 3. Gas-phase reactions of fluoride ion with 2-chloropropane and 1-chloropropane. The effect of methyl substituents. Journal of the American Chemical Societydoi:10.1021/ja00055a039
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
