• Phenyl Chloroformate (CAS 1885-14-9) - TCI C0649 - AMI Scientific
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TCI

CAS 1885-14-9

Phenyl Chloroformate TCI C0649

Phenyl Chloroformate TCI C0649
Rp 610.050,00
Rp 610.050,00
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TCI C0649 Phenyl Chloroformate is a highly reactive liquid acylating reagent used to convert amines and alcohols into carbamates and carbonates under mild conditions. The resulting phenoxycarbonyl group serves both as a temporary protecting group and as an effective leaving group, making it central to unsymmetrical urea synthesis. This two-step strategy is widely applied in medicinal chemistry to build compound libraries with diverse amine substituents. Supplied by AMI Scientific in 25 mL, 100 mL, and 500 mL sizes, the reagent is corrosive and moisture sensitive and must be handled in a fume hood.

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  • Terraza et al. (2004). Synthesis and characterization of 4,4??(dimethylsilylene) bis( phenyl chloroformate) and 4,4??(dimethylgermylene)bis(phenyl chloroformate) and their use in the synthesis of poly(urethanes). Polymer Bulletin doi:10.1007/s00289-004-0267-z
  • Lezama et al. (2015). Kinetic and Mechanisms of the Homogeneous, Unimolecular Elimination of Phenyl Chloroformate andp‐Tolyl Chloroformate in the Gas Phase. International Journal of Chemical Kinetics doi:10.1002/kin.20939
  • Imori et al. (2007). Efficient Demethylation of N,N‐Dimethylanilines with Phenyl Chloroformate in Ionic Liquids.. ChemInform doi:10.1002/chin.200707039

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.

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