TCI C0723 Hexyl Chloroformate (CAS 6092-54-2) is a six-carbon alkyl chloroformate offered by Tokyo Chemical Industry as a non-heterocyclic building block. It reacts readily with amines, alcohols, and phenols to deliver carbamates and mixed carbonates in a single, straightforward step. Analysts also use it to derivatise polar amino compounds ahead of chromatographic separation. Available from AMI Scientific in 5 mL and 25 mL packs, it must be handled in a fume hood and kept tightly closed away from moisture.
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- Hložek et al. (2016). Gabapentin, Pregabalin and Vigabatrin Quantification in Human Serum by GC–MS After Hexyl Chloroformate Derivatization. Journal of Analytical Toxicology doi:10.1093/jat/bkw070
- Kumar Yadav (2016). Application of an LC-MS/MS Method in Quantification of Hexyl Chloroformate Content in Dabigatran Etexilate Mesylate. Journal of Pharmaceutics & Drug Delivery Research doi:10.4172/2325-9604.1000154
- Angelino et al. (1998). Improved procedure for n-hexyl chloroformate-mediated derivatization of highly hydrophilic substances directly in water: hydroxyaminic compounds. Journal of Chromatography A doi:10.1016/s0021-9673(97)00911-4
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