TCI
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Description
TCI C1005 4-(Trifluoromethyl)benzonitrile (CAS 455-18-5) is the para isomer of the trifluoromethylbenzonitrile family, giving a linear, electron-poor aromatic building block with a well-defined dipole. Its nitrile group is readily converted into 4-(trifluoromethyl)benzoic acid, the corresponding benzylamine, tetrazoles, or aryl ketones via organometallic addition. The absence of steric interaction between the two substituents makes reactions on this scaffold clean and predictable, which suits routine synthetic work. AMI Scientific offers 5 g and 25 g packs; handle in a fume hood and store tightly closed in a cool, dry, well-ventilated place.
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