TCI
Dimethyldioctadecylammonium Iodide TCI D4124
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Description
TCI D4124 Dimethyldioctadecylammonium Iodide is a quaternary ammonium salt that carries two long alkyl chains of eighteen carbon atoms each, two methyl groups, and an iodide ion as the counter anion. Its structure — a permanently positively charged head group paired with two long hydrophobic tails — makes it both a cationic surfactant and a phase transfer catalyst. In the laboratory, this compound serves to carry ionic reagents from the aqueous phase into the organic phase, allowing reactions between substances that would normally not mix to proceed at a far higher rate without requiring expensive polar aprotic solvents.
The property that makes this material a preferred choice is the permanent positive charge on the nitrogen atom, which does not depend on pH and therefore keeps its activity stable across a wide range of reaction conditions. The two octadecyl chains impart very strong lipophilic character, so the ion pairs formed dissolve readily in non-polar organic solvents. This double-tailed structure also gives the compound a tendency to form bilayer structures and vesicles in water, unlike single-tailed surfactants that form spherical micelles. The iodide counter anion is easily polarizable and relatively loosely bound, which supports its role in ion pair exchange.
In Indonesian laboratories, this reagent is typically used in synthetic organic chemistry work where a two-phase reaction system needs to be driven efficiently, in surfactant and colloid studies, and in research groups preparing vesicle or bilayer systems. It is supplied by AMI Scientific as a research-grade TCI reagent for university, institutional, and industrial research laboratories that require consistent quality for reproducible synthetic and physicochemical work.
Laboratory Applications
- Phase transfer catalysis in two-phase synthesis — the permanent cationic head pairs with aqueous ionic reagents and its strongly lipophilic tails carry them into the organic phase, raising reaction rates substantially.
- Substitution and alkylation reactions — by transporting anionic nucleophiles into non-polar solvents, it allows these transformations to proceed without costly polar aprotic solvents that are otherwise needed to solubilise the reagent.
- Cationic surfactant studies — the compound acts as a cationic surfactant whose pH-independent positive charge makes it useful for investigating interfacial behaviour under widely varying solution conditions.
- Vesicle and bilayer preparation — the double-tailed molecular geometry favours formation of bilayer structures and vesicles in water rather than the spherical micelles produced by single-tailed surfactants.
- Ion pair exchange work — the easily polarizable and relatively loosely bound iodide counter anion makes this salt suitable for studies and procedures that depend on exchanging the associated anion.
Specifications
- Brand: TCI (Tokyo Chemical Industry)
- CAS Number: 7206-39-5
- Category: Chemistry > Synthetic Reagents > Phase Transfer Catalysts
- Chemical class: Quaternary ammonium salt; cationic surfactant and phase transfer catalyst
- Pack sizes: Available in standard TCI catalogue pack sizes; please confirm the required size when ordering
- Storage: Store in a tightly closed container in a cool, dry place away from moisture
Handling and Storage
Store this reagent in its original tightly closed container in a cool, dry, well-ventilated area, protected from moisture, since quaternary ammonium salts are generally hygroscopic and can absorb atmospheric water. Keep the container sealed between uses and reclose it promptly after weighing. Use chemically compatible glass or suitable plastic containers for transfers, and handle the material in a fume hood where practical. Standard laboratory personal protective equipment — safety glasses, gloves, and a lab coat — should be worn during handling, and spilled material should be cleaned up promptly. Always consult the manufacturer's safety data sheet before use and follow institutional waste disposal procedures.
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