TCI E0064 Ethylbenzene is a simple aromatic hydrocarbon compound built from a single benzene ring with an ethyl group attached to it, and it presents as a clear, colourless liquid with a characteristic aromatic odour. In the laboratory setting, this material holds an important position as a non-heterocyclic building block that serves as the starting point for a variety of aromatic substitution, oxidation, and dehydrogenation reactions. Its role does not stop at synthesis alone; ethylbenzene is also routinely used as a non-polar organic solvent and as a reference compound in analytical work involving the separation of aromatic hydrocarbon mixtures.
The characteristics that make ethylbenzene a preferred choice lie in its combination of measurable reactivity and easily managed physical properties. Its aromatic ring is sufficiently electron-rich to be responsive to electrophilic substitution reactions, while the ethyl group on the side chain provides a benzylic position that is susceptible to both oxidation and radical halogenation, thereby opening two distinct transformation pathways from one and the same molecule. As a solvent, its non-polar nature and immiscibility with water simplify extraction steps and phase separation.
In Indonesian laboratories, ethylbenzene of this grade is typically drawn upon in organic synthesis work where a non-heterocyclic aromatic starting material is required, and in analytical laboratories that handle aromatic hydrocarbon mixtures and need a dependable reference compound for separation work. Because it functions equally well as a reaction substrate and as a working non-polar solvent, it tends to be held as a general-purpose item on the organic chemistry shelf rather than reserved for a single procedure.
- Electrophilic aromatic substitution studies — the electron-rich benzene ring responds predictably to electrophilic attack, making this compound a straightforward substrate for teaching and developing substitution chemistry.
- Benzylic oxidation reactions — the ethyl side chain presents an accessible benzylic position that is readily susceptible to oxidation, offering a clean route to further functionalised aromatic products.
- Radical halogenation work — the same benzylic position is vulnerable to radical halogenation, allowing a second and chemically distinct transformation pathway to be explored from a single starting molecule.
- Dehydrogenation chemistry — as a non-heterocyclic aromatic building block, ethylbenzene serves as a recognised starting point for dehydrogenation procedures carried out on the side chain.
- Non-polar solvent and analytical reference — its non-polar character and immiscibility with water assist extraction and phase separation, while it also acts as a reference compound in aromatic hydrocarbon separation.
| Brand | TCI (Tokyo Chemical Industry) |
|---|---|
| CAS number | 100-41-4 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Non-Heterocyclic Building Blocks |
| Pack sizes | available in the standard laboratory pack sizes offered for this catalogue item; please confirm the currently available option when ordering |
| Physical form | clear, colourless liquid with a characteristic aromatic odour |
| Storage | keep in a tightly closed container, away from heat and ignition sources |
- Product code: TCI E0064
Store ethylbenzene in a tightly closed container in a cool, well-ventilated area, kept clearly away from heat, sparks, open flames, and other ignition sources. Containers appropriate for non-polar organic solvents — such as amber glass bottles or the supplier's original packaging — are suitable, and closures should be checked so the aromatic vapour is not released into the workspace. Handle the material inside a fume hood, since it is a volatile organic liquid with a noticeable aromatic odour, and wear standard laboratory protection including safety glasses, a lab coat, and solvent-resistant gloves. Keep it separated from strong oxidising agents, transfer only the quantity needed for immediate work, and return the stock container to its designated flammable-solvent storage location promptly after use.
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