Flurbiprofen is a chemical compound classified as a non-steroidal anti-inflammatory drug (NSAID). It plays a crucial role in biochemical and chemical experiments by inhibiting the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. These prostaglandins are key mediators in inflammatory processes and pain signaling. As a result, Flurbiprofen is widely used in research settings to study inflammation mechanisms and the development of new therapeutic agents. Its chemical stability and solubility in organic solvents make it a versatile reagent for various laboratory applications.
Flurbiprofen is preferred due to its chemical stability and solubility in organic solvents such as ethyl acetate and acetone. Its complex molecular structure enables diverse chemical reactions under different conditions, making it suitable for precise and consistent experimental outcomes. Additionally, Flurbiprofen exhibits strong inhibitory activity against specific enzymes, making it ideal for enzyme and inhibitor studies. These properties ensure that it remains a reliable and effective reagent in both biochemical and pharmaceutical research.
In Indonesian laboratories, Flurbiprofen is commonly used in drug research, quantitative analysis, and biological activity testing. It is also employed in the study of anti-inflammatory mechanisms and the development of more effective and safer compounds. Its versatility and reliability make it a preferred choice for researchers working in various scientific fields, including pharmacology and biochemistry.
Advantages (TCI brochure)
- Inhibited Dansylglycine and BD140 binding to HSA site II in brochure testing
TCI brochures (PDF)
- Fluorescent Probes for the Characterization of Two Specific Drug Binding Sites on HSA 2025-04-01 · p. 4
- Regenerative Medicine Research Reagents 2016-03-18 · p. 1
- Anti-Rheumatoid Arthritis Ingredients 2025-01-29 · p. 1
- Lipid Mediator Research Reagents 2026-04-10 · p. 1
- Immune System, Inflammation, Allergy Research Reagents 2025-05-26 · p. 3
- Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 33
- Drug research and development: Flurbiprofen is used to study the pharmacological effects of NSAIDs and to develop new therapeutic agents with improved efficacy and safety profiles.
- Quantitative analysis: It serves as a standard compound for quantitative assays, enabling accurate measurement of drug concentrations in biological samples.
- Biological activity testing: Flurbiprofen is utilized to evaluate the inhibitory effects on enzymes such as COX, which are critical in inflammatory processes.
- Enzyme inhibition studies: Its strong inhibitory activity makes it suitable for investigating enzyme mechanisms and the development of enzyme inhibitors.
- Inflammation mechanism research: It is used to explore the molecular pathways involved in inflammation and pain, aiding in the understanding of disease progression.
From the TCI brochure
- Site II drug in HSA binding assay
| Brand | TCI |
|---|---|
| CAS number | 5104-49-4 |
| Molecular formula | — |
| Purity | — |
| Category | Life Science > Biochemicals and Reagents > Enzymes, Enzyme Inhibitors, Enzyme Substrates |
| Pack sizes | — |
| Physical form | — |
| Storage | Store in a cool, dry place away from light |
Flurbiprofen should be stored in a cool, dry place away from direct light to maintain its chemical stability. It is recommended to use airtight containers to prevent moisture absorption and contamination. Due to its potential reactivity, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles. In laboratory settings, it is important to ensure proper ventilation when working with this compound. Avoid exposure to incompatible substances to prevent unwanted chemical reactions. Proper storage and handling practices help preserve the integrity and effectiveness of Flurbiprofen in research applications.
References cited in the TCI brochure
- Jamie Ghuman. Structural Basis of the Drug-binding Specificity of Human Serum Albumin Journal of Molecular Biology, 2005. doi:10.1016/j.jmb.2005.07.075
- Masaki OTAGIRI. Study on Binding of Drug to Serum Protein YAKUGAKU ZASSHI, 2009. doi:10.1248/yakushi.129.413
Product Categories
- Biochemicals and ReagentsEnzymes, Enzyme Inhibitors, Enzyme SubstratesEnzymes [by Application]
- Biochemicals and ReagentsEnzymes, Enzyme Inhibitors, Enzyme SubstratesEnzyme Inhibitors [Biochemicals and Reagents]
- Biochemicals and ReagentsPharmaceutical Research Reagents (for Experimental Use)Anti-inflammatory Ingredients (for Research and Experimental Use)
- Biochemicals and ReagentsPharmaceutical Research Reagents (for Experimental Use)Anti-rheumatoid Arthritis Ingredients (for Research and Experimental Use)
- Biochemicals and Reagents
- Cell BiologyImmune System, Inflammation, Allergy ResearchCyclooxygenase (COX) Inhibitors
- Pharmaceutical Development and Drug Discovery ResearchPharmaceutical Research Reagents (for Experimental Use)Anti-inflammatory Ingredients (for Research and Experimental Use)
- Pharmaceutical Development and Drug Discovery ResearchPharmaceutical Research Reagents (for Experimental Use)Anti-rheumatoid Arthritis Ingredients (for Research and Experimental Use)
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