5-Fluoro-1-indanone is a chemical compound widely used as a building block in the synthesis of complex organic compounds. Its unique molecular structure, featuring a fluorine group at the 5-position and an indan ring, makes it a valuable reagent in various chemical processes. In laboratory settings, this compound plays a crucial role in the development of pharmaceuticals, cosmetics, and bioactive molecules. Its versatility and functional group compatibility allow chemists to design and synthesize a wide range of target compounds with high efficiency.
The compound is favored for its stable chemical properties and controlled reactivity, which enable it to participate in substitution and oxidation reactions without significant degradation. It exhibits good solubility in organic solvents such as ethyl acetate and chloroform, making it easy to handle and incorporate into synthetic protocols. These characteristics make it a preferred choice for researchers working in organic chemistry, as it supports the creation of complex structures with minimal side reactions.
In Indonesian laboratories, 5-Fluoro-1-indanone is commonly used by researchers in organic chemistry, pharmacy, and biochemistry. Its application spans from academic research to industrial development, supporting the synthesis of compounds with specific biological activities. Due to its reliability and effectiveness, it remains a key reagent in both small-scale and medium-scale chemical synthesis projects.
TCI brochures (PDF)
- Fluorination Reagents, Fluorinated Building Blocks 2026-03-18 · p. 27
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- Organic synthesis is a primary application where 5-Fluoro-1-indanone is used to introduce fluorine atoms into complex molecular frameworks, enhancing the reactivity and selectivity of target compounds.
- Pharmaceutical research benefits from this compound as it serves as a key intermediate in the development of drug molecules with improved pharmacological properties and bioavailability.
- Cosmetic formulation involves the use of 5-Fluoro-1-indanone to create compounds with specific functional properties, such as UV protection or skin compatibility, in personal care products.
- Biochemical studies rely on this compound to synthesize molecules with biological activity, enabling research into enzyme interactions and molecular mechanisms.
- Analytical chemistry applications include the use of 5-Fluoro-1-indanone as a standard for calibration and identification in chromatographic and spectroscopic analyses.
| Brand | TCI |
|---|---|
| CAS number | 700-84-5 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Fluorinated Building Blocks |
| Pack sizes | Available in various quantities as per standard laboratory supply |
| Physical form | Solid or liquid, depending on the specific product variant |
| Storage | Store in a cool, dry place away from direct sunlight and moisture |
5-Fluoro-1-indanone should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to use airtight containers made of glass or high-density polyethylene to minimize exposure to moisture and air. Due to its reactivity, it should be handled in a well-ventilated area, with appropriate personal protective equipment such as gloves and safety goggles. Avoid contact with incompatible substances like strong oxidizing agents. Regularly check the container for any signs of damage or leakage to ensure safe storage. Proper labeling and storage conditions are essential to maintain the integrity of the compound during laboratory use.
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