Disodium alpha-Glycerophosphate TCI G0096

Chemical Identity

Other names: alpha-Glycerophosphoric Acid Disodium Salt
CAS No.: 1555-56-2
Formula: C3H7Na2O6P
Molecular weight: 216.04 g/mol
Purity: >85.0%(T)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: disodium;2,3-dihydroxypropyl phosphate
SMILES: C(C(COP(=O)([O-])[O-])O)O.[Na+].[Na+]
InChIKey: GEKBIENFFVFKRG-UHFFFAOYSA-L
MDL: MDL00035539
PubChem: CID 14754

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TCI G0096 Disodium alpha-Glycerophosphate is the disodium salt of glycerol-1-phosphoric acid, a glycerophosphate in which the phosphate group is attached to a terminal carbon of the glycerol backbone. This alpha isomer forms the structural core of the glycerophospholipids that make up cell membranes, which makes the compound an important reference material and precursor in lipid metabolomics research. In the laboratory it also serves as a water-soluble source of organic phosphate and as a standard substrate for measuring phosphatase enzyme activity.

The property that leads researchers to select the alpha isomer specifically is its clearly defined phosphate position, which allows metabolic pathways and enzyme specificity to be distinguished unambiguously from the beta isomer. As a disodium salt, the material presents as a white powder that dissolves readily in water and yields a clear working solution that can be prepared without organic solvents. That high solubility makes it straightforward to prepare stock solutions at concentrations adequate for enzyme assays, while the powder form allows precise weighing in experiments that demand a high degree of accuracy.

Biochemistry, cell biology and microbiology laboratories across Indonesia use this material in routine assay work and in research projects where a well-characterised glycerophosphate reference is required. It fits naturally into laboratories that already run phosphatase activity measurements, lipid metabolism studies and membrane-related investigations, since it can be handled with ordinary aqueous buffer preparation and standard analytical balances rather than specialised solvent handling equipment.

Phosphatase activity assays: serves as a standard organic phosphate substrate whose released phosphate can be measured to quantify alkaline or acid phosphatase activity reproducibly.
Lipid metabolomics research: acts as a defined reference compound for the glycerophosphate backbone, supporting identification and quantification of glycerophospholipid-related metabolites in analytical workflows.
Glycerophospholipid precursor studies: provides the alpha-isomer core structure used to trace how cells build membrane phospholipids from glycerol-phosphate starting material in metabolic experiments.
Enzyme specificity characterisation: its unambiguous phosphate position lets researchers separate alpha-selective from beta-selective enzyme behaviour, clarifying substrate preference in comparative biochemical studies.
Culture and buffer supplementation: supplies a highly water-soluble organic phosphate source for microbiological and cell biology media where organic rather than inorganic phosphate is required.

Brand	TCI
CAS number	1555-56-2
Molecular formula	—
Purity	—
Category	Life Science > Cell Biology > Metabolomics
Pack sizes	please refer to the available TCI catalogue pack configurations for this item
Physical form	white powder, readily soluble in water
Storage	keep in a tightly closed container in a cool, dry place

Store the container tightly closed in a cool, dry place, away from direct sunlight and sources of moisture, since the powder form is best protected from humidity that could cause caking and affect weighing accuracy. Original manufacturer packaging or a clean, well-sealed glass or chemically compatible plastic container is suitable for storage and for any repackaged portions, which should be clearly labelled. Handle the powder in a well-ventilated area or fume hood to avoid inhaling dust, and wear a laboratory coat, safety glasses and gloves during weighing and solution preparation. Use clean, dry spatulas to prevent contamination of the bulk material, close the container promptly after dispensing, and wash hands after handling. Prepare aqueous solutions with laboratory-grade water and follow your institution's standard procedures for chemical waste disposal.

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