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TCI

CAS 100-97-0

Hexamethylenetetramine TCI H0093

Hexamethylenetetramine TCI H0093

Chemical Identity

Other names
HMTA · 1,3,5,7-Tetraazaadamantane · HMTA · Urotropine · Methenamine
CAS No.
100-97-0
PubChem
CID 4101·SID 87570541
Formula
C6H12N4
Molecular weight
140.19 g/mol
Purity
>99.0%(GC)(T)
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane
SMILES
C1N2CN3CN1CN(C2)C3
InChIKey
VKYKSIONXSXAKP-UHFFFAOYSA-N
MDL
MDL00006895
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Hexamethylenetetramine (HMT), with CAS number 100-97-0, is a versatile chemical compound widely used in laboratory settings. As a key building block in the synthesis of heterocyclic compounds, HMT plays a crucial role in the development of complex molecules with ring structures. Its ability to act as a reagent or reaction modifier makes it an essential component in various synthetic pathways. This compound is commonly employed in reactions requiring a stabilizing agent or a reaction control element, contributing to the efficiency and success of chemical processes.

HMT is valued for its chemical stability and reactivity with a range of substances, including acids and bases. These properties make it an ideal choice for reactions that require pH control or precise reaction conditions. Its high melting point ensures thermal stability, making it suitable for use in high-temperature laboratory environments. Additionally, its inert nature allows it to be used in a variety of chemical applications without interfering with the desired reaction outcomes.

In Indonesian laboratories, HMT is extensively used in chemical research, pharmaceutical development, and organic synthesis. It is also a common material in educational settings, supporting practical chemistry experiments that require fundamental reagents. Due to its broad applicability, HMT remains a critical material in both academic and industrial laboratory environments across Indonesia.

TCI brochures (PDF)

  • Chemical synthesis: Hexamethylenetetramine is widely used in the synthesis of heterocyclic compounds due to its ability to act as a reagent and reaction modifier.
  • Pharmaceutical development: HMT is an essential component in the creation of complex organic molecules, supporting drug development and compound testing.
  • Organic chemistry research: Its stability and reactivity make it ideal for use in various organic reactions requiring controlled conditions.
  • Educational laboratories: HMT is commonly used in chemistry practical sessions to teach fundamental concepts and reaction mechanisms.
  • Industrial chemical processes: Its thermal stability and reactivity make it suitable for use in industrial-scale chemical manufacturing and processing.

From the TCI brochure

  • Duff reaction: formylation of phenol derivatives (H0093 / AcOH, then H3O+)

Brand TCI
CAS number 100-97-0
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes Available in various quantities as per standard laboratory supply
Physical form Solid
Storage Store in a cool, dry place away from direct sunlight and moisture

Data from the TCI brochure

Ukuran kemasan25g / 500g

Source: TCI brochure RR031 (2024-07-08)

Hexamethylenetetramine should be stored in a cool, dry place, away from direct sunlight and moisture. It is recommended to use airtight containers to prevent exposure to humidity, which may affect its stability. As a solid, it should be kept in a well-ventilated area to ensure safe handling. Avoid contact with incompatible materials such as strong acids or bases. Always wear appropriate personal protective equipment, including gloves and safety goggles, when handling this compound. Proper storage and handling practices are essential to maintain the integrity of the material and ensure laboratory safety.

References cited in the TCI brochure

  1. Y. Ogata. Kinetics and mechanism of the Duff reaction Tetrahedron, 1968. doi:10.1016/s0040-4020(01)88408-8