2-Hydroxy-5-methylisoindoline-1,3-dione TCI M3571

Chemical Identity

CAS No.: 173962-59-9
Purity: >98.0%(HPLC)(T)

Rp 1.246.350,00

~~Rp 887.250,00~~ Rp 1.246.350,00

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Berat 1g 5g

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2-Hydroxy-5-methylisoindoline-1,3-dione is a chemical compound widely used in research applications within organic and biochemical laboratories. It serves as a key intermediate in the synthesis of complex molecules, particularly in the development of bioactive compounds and peptides. This compound is essential for researchers aiming to create molecules with specific biological activities, such as pharmaceuticals or therapeutic agents. Its presence in laboratory workflows supports the advancement of chemical biology and medicinal chemistry by enabling the construction of complex molecular frameworks.

The compound’s unique chemical structure, featuring two carbonyl groups and one hydroxyl group, contributes to its reactivity and polarity. These properties make it highly suitable for chemical reactions involving substitution and condensation processes. Its ability to participate in a variety of synthetic pathways enhances its utility in laboratory settings, where versatility and reactivity are critical. The compound’s chemical profile allows it to be a valuable tool for researchers working on the development of new bioactive substances.

In Indonesian laboratories, 2-Hydroxy-5-methylisoindoline-1,3-dione is commonly used in biochemical and pharmacological research. It is a staple in academic and research institutions, where it is employed to study the mechanisms of biological activity in various compounds. Its role in the synthesis of bioactive molecules makes it an important component in the pursuit of scientific discovery and innovation within the local scientific community.

Advantages (TCI brochure)

Enables synthesis of redox-active esters by condensation with carboxylic acids
Obtained RAEs are applicable to C(sp2)-C(sp3) cross-coupling reactions

TCI brochures (PDF)

N-Hydroxyphthalimide Derivatives for the Synthesis of Redox Active Esters 2024-02-06 · p. 1
Condensing Agents 2025-11-18 · p. 6

Related TCI products

Bioactive Compound Synthesis: This compound is ideal for synthesizing bioactive molecules due to its reactive functional groups and structural versatility, making it a key reagent in pharmaceutical research.
Peptide Chemistry Research: Its ability to participate in condensation reactions makes it suitable for peptide synthesis, supporting studies in protein structure and function.
Organic Synthesis Applications: The compound’s polar nature and reactivity make it a valuable intermediate in the synthesis of complex organic molecules.
Pharmacological Studies: It is frequently used in drug development to explore the chemical pathways of bioactive substances and their biological effects.
Chemical Biology Investigations: Its structural complexity supports research into molecular interactions and biochemical mechanisms in living systems.

From the TCI brochure

Decarboxylative cross-coupling between small-ring alkyl carboxylic acid active ester and aryl bromide

Brand	TCI
CAS number	173962-59-9
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes	As available from supplier
Physical form	Solid (as per standard product description)
Storage	Store in a cool, dry place away from light

Data from the TCI brochure

Ep (vs. Fc+/Fc) of RAE	-1.704 V (RAE with R = phenylcyclopropyl group as drawn in brochure)

Source: TCI brochure RR190 (2024-02-06)

This compound should be stored in a cool, dry environment, away from direct sunlight and sources of heat. It is recommended to use airtight containers to prevent moisture absorption and contamination. Due to its reactive nature, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. It is important to ensure proper ventilation in the laboratory when working with this compound to minimize exposure. Avoid contact with incompatible materials, and follow standard laboratory safety protocols to ensure safe handling and storage.

References cited in the TCI brochure

Daniel C. Salgueiro. Control of Redox‐Active Ester Reactivity Enables a General Cross‐Electrophile Approach to Access Arylated Strained Rings** Angewandte Chemie International Edition, 2022. doi:10.1002/anie.202205673