DL-3-Pyrrolidinol from TCI is the racemic mixture of 3-hydroxypyrrolidine. It is a five-membered nitrogen heterocycle with a hydroxyl group at the 3-position. The compound is a heterocyclic building block used widely in organic synthesis and medicinal chemistry. The pyrrolidine scaffold appears often in drug molecules and natural products. This makes DL-3-Pyrrolidinol a practical starting material for building more complex structures, especially when researchers do not yet need an enantiomerically pure form.
The main advantage of DL-3-Pyrrolidinol is that one small molecule carries two different functional groups: a secondary amine in the ring and a secondary alcohol. Each group can be modified selectively. For example, the nitrogen can be protected with a Boc or Cbz group, and the hydroxyl group can then be oxidized, etherified, or converted into a leaving group. This flexibility makes the compound an efficient starting point for many substituted pyrrolidine derivatives. Because it is racemic, it also suits method development, chiral resolution studies, and the synthesis of racemic reference compounds.
In Indonesia, DL-3-Pyrrolidinol is relevant to synthetic organic chemistry laboratories at universities, research institutes, and pharmaceutical research and development teams. Research groups use it to explore new heterocyclic scaffolds, to train students in protecting-group strategy and functional-group conversion, and to prepare racemic standards before moving to enantiopure material. AMI Scientific supplies this TCI product to laboratories that need a dependable, well-characterized building block for their synthesis work.
Related TCI products
- Heterocyclic scaffold synthesis: the pyrrolidine ring with a 3-hydroxyl group gives a ready-made core for building substituted pyrrolidines found in drug-like molecules and natural products.
- Medicinal chemistry intermediate preparation: the secondary amine and secondary alcohol can be modified one at a time, which lets chemists create varied analogues for structure–activity studies.
- Protecting-group and functional-group conversion studies: N-protection with Boc or Cbz, followed by oxidation, etherification, or conversion of the hydroxyl to a leaving group, makes it a useful teaching and research substrate.
- Chiral resolution and method development: as a racemic mixture, it is a suitable test substrate for developing resolution methods and chiral separation conditions before enantiopure material is used.
- Racemic reference compound synthesis: it lets researchers prepare racemic versions of target pyrrolidine derivatives to use as analytical comparisons alongside enantiomerically pure products.
| Brand | TCI (product code P1083) |
|---|---|
| CAS number | 40499-83-0 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Heterocyclic Building Blocks |
| Pack sizes | available in the standard pack sizes offered by TCI for this product code |
| Physical form | refer to the TCI product specification and certificate of analysis |
| Storage | keep tightly closed in a cool, dry place, following the TCI label and safety data sheet |
Store DL-3-Pyrrolidinol in its original, tightly sealed container, in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep it away from strong oxidizing agents and acids, because the compound contains both an amine and an alcohol group. Reseal the container promptly after use to limit exposure to air and moisture. Handle the material in a fume hood. Wear suitable personal protective equipment, including chemical-resistant gloves, safety glasses, and a laboratory coat. Avoid contact with skin and eyes, and do not inhale vapors or dust. Read the TCI safety data sheet before use, and dispose of waste according to institutional and local chemical waste regulations.
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