Polyethylene Glycol 11000 TCI P2829

Chemical Identity

CAS No.: 25322-68-3

Rp 477.750,00

~~Rp 333.900,00~~ Rp 477.750,00

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Polyethylene Glycol 11000 (PEG 11000) is a polyethylene glycol with a nominal average molecular weight of about 11,000, which places it among the high-molecular-weight PEGs. TCI supplies it under product code P2829, listed in the Chemical Biology category under PEGylation. Like other PEGs, the polymer is made of repeating ethylene oxide units with a hydroxyl group at each end of the chain. In the laboratory, long-chain PEGs like this one are used when researchers need a larger hydrodynamic effect, for example in macromolecular crowding studies, biomolecule precipitation, or building polymer matrices.

PEG 11000 has a much longer chain than liquid or semi-solid PEGs. As a result, it is usually a solid at room temperature and gives more viscous solutions. These traits help in applications that depend on excluded volume, such as precipitating proteins or DNA and mimicking the crowded environment inside living cells. When grafted onto surfaces, the long chain also forms a thicker hydration layer, which helps reduce unwanted protein adsorption. It still dissolves well in water, so researchers can prepare it in common aqueous buffers without much effort. This mix of high molecular weight, good water solubility and a simple, well-defined chemical structure makes it a dependable choice for biochemical and materials work.

In Indonesian laboratories, PEG 11000 is mainly used in university biochemistry and molecular biology departments, research institutes and pharmaceutical development groups. Researchers there use it to precipitate and concentrate nucleic acids and proteins, to study crowding effects on enzyme activity and protein folding, and to modify surfaces in biomaterials and nanoparticle projects. Its role in PEGylation-related research also makes it useful for teams looking at how polymer chain length affects stability, solubility and nonspecific binding in their experiments.

TCI brochures (PDF)

Biomaterials Research Reagents 2025-02-19 · p. 6

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Macromolecular crowding studies: its long chain and large hydrodynamic volume let researchers mimic the dense environment inside cells when studying enzyme kinetics, protein folding and molecular interactions.
Protein and DNA precipitation: the excluded-volume effect of high-molecular-weight PEG pushes biomolecules out of solution, so it is a practical agent for concentrating and recovering proteins or nucleic acids.
Surface passivation and PEGylation research: once grafted onto surfaces or particles, the long chains form a thick hydration layer that reduces nonspecific protein adsorption on sensors, beads and biomaterials.
Polymer matrix and hydrogel formation: the hydroxyl groups at both chain ends and the high molecular weight make it a suitable building block for polymer networks, matrices and related materials research.
Viscosity and solution-property studies: it produces more viscous aqueous solutions than shorter PEGs, which makes it useful for studying how chain length affects rheology, diffusion and the behavior of formulations.

Brand	TCI (product code P2829)
CAS number	25322-68-3
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > PEGylation
Pack sizes	as offered by TCI for product P2829; please contact AMI Scientific to confirm available options
Physical form	generally a solid at room temperature (high-molecular-weight PEG)
Storage	keep tightly closed in a cool, dry place, following the TCI label and SDS

Store PEG 11000 in its original, tightly sealed container in a cool, dry and well-ventilated area, away from direct sunlight, heat sources and strong oxidizing agents. PEG can absorb moisture from the air, so close the container promptly after each use to protect the material's quality. If you transfer it, use clean, dry, chemically compatible containers such as glass or suitable plastic bottles, and label them clearly. During handling, follow standard laboratory practice: wear gloves, safety glasses and a lab coat, avoid creating or breathing in dust when weighing the solid, and clean up spills quickly to keep floors from becoming slippery. Prepare solutions with clean glassware, and store aqueous stocks under the right conditions to limit microbial growth. Always check the TCI Safety Data Sheet for full hazard, storage and disposal guidance, and dispose of waste according to local regulations.

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