Polyethylene Glycol 20000 TCI P2830

Chemical Identity

CAS No.: 25322-68-3

Rp 477.750,00

~~Rp 333.900,00~~ Rp 477.750,00

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Berat 25g 500g

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Polyethylene Glycol 20000 (PEG 20000) is a polyethylene glycol with a nominal average molecular weight of about 20,000. It is one of the most widely used high-molecular-weight PEG grades. TCI supplies it under product code P2830 in its Chemical Biology range, in the PEGylation category. The polymer is made of repeating ethylene oxide units with hydroxyl groups at the chain ends. In the laboratory, PEG 20000 is used to concentrate dialysates, precipitate biomolecules and create molecular crowding. It is also a starting material for long-chain PEG conjugates in drug delivery research.

Its very long chains give PEG 20000 strong osmotic and excluded-volume effects. Because the molecule is large, it does not pass easily through many dialysis membranes. This means it can be placed outside a dialysis bag to draw water out and gently concentrate protein samples. In PEGylation, the long chain increases the hydrodynamic size of the conjugated molecule, a strategy widely studied for extending the circulation time of therapeutic compounds. The solid dissolves well in water, though its solutions become fairly viscous at high concentrations.

In Indonesia, PEG 20000 is useful for biochemistry laboratories, protein research groups and university research teams working on biomolecule purification and characterization. It also serves pharmaceutical and drug delivery research laboratories that study polymer conjugates and long-chain PEG systems. Researchers in molecular biology and structural studies use it for crowding experiments and sample concentration. Its role in PEGylation makes it relevant for academic and industrial groups developing biomaterials and polymer-based formulations.

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Biomaterials Research Reagents 2025-02-19 · p. 6

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Dialysate concentration: PEG 20000 does not pass easily through many dialysis membranes, so it can be placed outside the dialysis bag to draw water out and gently concentrate protein samples.
Biomolecule precipitation: its strong excluded-volume effect makes PEG 20000 a useful precipitant for proteins and other biomolecules during purification and sample preparation.
Macromolecular crowding studies: the long polymer chains mimic crowded cellular conditions, letting researchers study how crowding affects protein folding, binding and enzyme behavior in vitro.
PEGylation and conjugate synthesis: PEG 20000 is a starting material for long-chain PEG conjugates, which increase the hydrodynamic size of attached molecules in drug delivery research.
Drug delivery research: long-chain PEGylation is widely studied as a way to extend the circulation time of therapeutic compounds, which makes PEG 20000 relevant to formulation and pharmaceutical studies.

Brand	TCI (product code P2830)
CAS number	25322-68-3
Molecular formula	approximately 20,000
Purity	—
Category	Chemistry > Chemical Biology > PEGylation
Pack sizes	see the product listing for available pack sizes, and follow the supplier's label and Safety Data Sheet for storage conditions
Physical form	Solid, readily soluble in water
Storage	—

Keep PEG 20000 in a tightly closed original container in a cool, dry, well-ventilated place, away from moisture and direct sunlight. Close the container firmly after each use so the solid does not absorb moisture from the air. Use clean, dry spatulas and glassware or compatible plastic containers when weighing and preparing solutions. Because concentrated solutions can be viscous, allow enough time for the solid to dissolve fully. Follow standard laboratory practice: wear gloves, safety glasses and a lab coat, avoid creating dust, and don't eat or drink in the work area. Always check the Safety Data Sheet for full handling and disposal guidance.

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