Sulfonfluorescein from TCI is a xanthene-class dye that is structurally the sulfonephthalein analogue of fluorescein. Fluorescein's framework carries a carboxylic acid group in its lactone form. In sulfonfluorescein, that position holds a sulfonic acid group in its sultone form. In the laboratory, this compound belongs to the photonic and optical materials group of xanthene dyes. Researchers use it as a fluorescent dye, as a model compound for photophysical studies, and as a starting material for more specialised dye derivatives.
Researchers choose this material for its rigid, conjugated xanthene framework, a feature shared by many strongly fluorescent dyes. Replacing the carboxylic acid group with a sulfonic acid group changes the compound's acidity and the equilibrium between its open and closed forms. This in turn affects how its colour and fluorescence respond to pH. Because the sulfonic acid group is strongly acidic, the coloured open form forms more readily than in fluorescein within certain pH ranges. These features make the compound useful as an indicator, as a comparison dye, and as a scaffold for designing new fluorescent probes.
In Indonesia, sulfonfluorescein is useful for analytical chemistry, photochemistry, materials science, and biochemistry laboratories at universities and research institutions. Academic groups can use it in teaching and research on structure–property relationships in dyes, especially to compare carboxylate and sulfonate xanthene systems. Research teams working on optical materials, fluorescent sensors, and spectroscopic methods can use it as a reference compound or synthetic precursor. Its TCI origin gives laboratories a well-documented reagent for reproducible experimental work.
Related TCI products
- Fluorescent dye studies: its rigid, conjugated xanthene framework makes it a suitable fluorescent dye for spectroscopic experiments and for comparing optical behaviour across related xanthene structures.
- Photophysical model research: researchers can use it as a model compound to study how replacing a carboxylic acid group with a sulfonic acid group changes absorption and emission behaviour.
- pH-responsive indicator work: because its sulfonic acid group shifts the balance between open and closed forms, its colour and fluorescence respond to pH in a way that suits indicator studies.
- Comparison dye alongside fluorescein: as the sulfonephthalein analogue of fluorescein, it is a natural comparison dye for experiments that isolate the effect of the acidic group on dye behaviour.
- Synthesis of new fluorescent probes: its xanthene scaffold serves as a starting material for more specialised dye derivatives and new probes for sensing and imaging research.
| Brand | TCI (product code S0132) |
|---|---|
| CAS number | 4424-03-7 |
| Molecular formula | — |
| Purity | — |
| Category | Materials Science > Photonic Materials and Optical Materials > Xanthene Dyes |
| Pack sizes | available in the pack sizes listed by TCI for this product code |
| Physical form | refer to the TCI product label and Safety Data Sheet |
| Storage | follow the storage conditions stated on the TCI label and Safety Data Sheet |
Store sulfonfluorescein in its original, tightly closed container in a cool, dry, well-ventilated place, away from direct light and moisture, unless the TCI label specifies other conditions. Keep it away from incompatible substances such as strong oxidising agents. Handle it in line with good laboratory practice: wear safety glasses, gloves, and a lab coat, avoid creating or inhaling dust, and prevent contact with skin and eyes. Work in a fume hood or ventilated area when weighing the powder or preparing solutions. Label any prepared solutions clearly. Always check the Safety Data Sheet supplied with the product for specific hazard, first aid, and disposal guidance before use.
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