Collection: Photolabile Protecting Groups

Photolabile Protecting Groups — compiles coumarin-based and nitrophenyl-based protecting groups, such as 7-(diethylamino)coumarin derivatives and 2-nitrophenyl-1-ethanol, that can be cleaved by light exposure at specific wavelengths. This class serves as a chemical tool for controlled release of functional groups in synthesis and chemical biology research.

These photolabile protecting groups are used by chemical biology researchers and organic synthesis chemists to protect reactive groups on molecules during synthesis steps, then release them in a controlled manner through light irradiation without requiring additional chemical reagents. Nitrobenzyl and coumarin derivatives are widely used in designing caged compounds for spatial and temporal studies of compound release in cellular research.

Example products in this collection: TCI B5008 1256259-14-9 4-(Bromomethyl)-7-(diethylamino)coumarin, TCI B5738 223420-41-5 6-Bromo-7-hydroxy-4-(hydroxymethyl)coumarin, TCI A3678 188891-18-1 4-(4-Acetyl-2-methoxy-5-nitrophenoxy)butanoic Acid, TCI B6668 1410809-16-3 tert-Butyl 4-[4-(1-Hydroxyethyl)-2-methoxy-5-nitrophenoxy]butanoate, TCI N1133 64987-77-5 2-(2-Nitrophenyl)propan-1-ol, TCI B6669 1410809-15-2 tert-Butyl 4-(4-Acetyl-2-methoxy-5-nitrophenoxy)butanoate, TCI N1132 3205-25-2 1-(2-Nitrophenyl)ethanol, TCI D4970 54711-38-5 7-(Diethylamino)-4-(hydroxymethyl)coumarin.

Pay attention to the release wavelength that matches the chromophore (coumarin or nitrophenyl), as well as the reactive groups on the molecule to be conjugated. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other related categories under Chemical Biology, often used together in one laboratory workflow:

• Peptide Chemistry
• Glycoscience
• Conjugation Chemistry/Click Chemistry
• Bioconjugation
• Linkers and Crosslinkers
• Nucleic Acid Chemistry

Back to Chemical Biology. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — the official TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.