Collection: Biotin Azides/Alkynes [Conjugation Chemistry/Click Chemistry]

Biotin Azides/Alkynes [Conjugation Chemistry/Click Chemistry] — compiles biotin derivatives functionalized with azide, alkyne, or tetrazine groups, typically via polyethylene glycol (PEG) linkers, so they are ready for use in azide-alkyne cycloaddition reactions as well as tetrazine-trans-cyclooctene ligation. The biotin group in their structure enables subsequent binding to streptavidin or avidin proteins.

Biotin Azides/Alkynes are used by chemical biology and biotechnology researchers to label biomolecules such as proteins, peptides, oligonucleotides, or lipids through click chemistry reactions that are selective and efficient under mild conditions. The resulting biotin-target conjugates are then captured using streptavidin resins or beads for purification, Western blot and ELISA-based detection, cell imaging, and protein-protein interaction studies in proteomics research.

Example products in this collection: TCI T4277 2-[4-(1,2,4,5-Tetrazin-3-yl)phenyl]-N-[2-[2-[2-(prop-2-yn-1-yloxy)ethoxy]ethoxy]ethyl]acetamide, TCI B5546 1309649-57-7 Biotin-PEG4-Azide, TCI A3420 908007-17-0 N-(3-Azidopropyl)biotinamide (2mg*5), TCI B6265 875770-34-6 Biotin-PEG3-Azide (2mg*5), TCI A3202 1426828-06-9 Azide-PEG3-Desthiobiotin, TCI B6266 1309649-57-7 Biotin-PEG4-Azide (2mg*5), TCI A2524 908007-17-0 N-(3-Azidopropyl)biotinamide, TCI B6511 1262681-31-1 Biotin-PEG4-Alkyne.

Pay attention to the type of reactive group (azide, alkyne, or tetrazine) to match the reaction pair, the length of the PEG linker which affects the steric distance of conjugation, as well as purity and small pack sizes for long-term stability. All products are original Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under Conjugation Chemistry/Click Chemistry, often used together in one laboratory workflow:

Back to Conjugation Chemistry/Click Chemistry. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official TCI Japan distributor in Indonesia — for stock availability checks and direct lead time from Japan.

4 products