Collection: Crosslinker Azides/Alkynes [Conjugation Chemistry/Click Chemistry]

Crosslinker Azides/Alkynes [Conjugation Chemistry/Click Chemistry] — compiles azide and alkyne derivatives, including strained-ring variants such as bicyclononyne derivatives, which function as complementary reactive groups in cycloaddition reactions. Also includes derivatives with oligo(ethylene glycol) arms or active ester groups to facilitate linking to biomolecules or material surfaces.

Azide/alkyne crosslinkers are used in click chemistry reactions such as CuAAC and SPAAC to selectively link two molecules without interfering with other functional groups, for example in protein-ligand conjugation, fluorescent probe labeling, or surface modification of materials and nanoparticles. Bioconjugation and materials chemistry researchers generally use this group to build complex molecular architectures in a stepwise and controlled manner.

Example products in this collection: TCI U0054 2777-65-3 10-Undecynoic Acid, TCI B6275 1426827-79-3 (1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl Succinimidyl Carbonate, TCI T3114 208827-90-1 Triethylene Glycol Mono(2-propynyl) Ether, TCI B6628 14044-63-4 But-3-yn-1-amine, TCI B4062 1263166-93-3 N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane, TCI C3904 CPO-PEG3-Alkyne, TCI B3790 199804-21-2 Bis[2-(4-azidosalicylamido)ethyl] Disulfide, TCI C3916 CPO-PEG3-DBCO (contains 5% Acetonitrile at maximum).

Pay attention to the type of reactive group (ordinary azide vs. strained alkyne for catalyst-free reactions), the length of the spacer arm, and additional functional groups such as active esters or disulfides, which determine compatibility with the conjugation target. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other categories parallel to Conjugation Chemistry/Click Chemistry, often used together in a single laboratory workflow:

• Terminal Alkynes [Conjugation Chemistry/Click Chemistry]
• Azides [Conjugation Chemistry/Click Chemistry]
• Catalysts, Ligands, Reagents [Conjugation Chemistry/Click Chemistry]
• Tetrazines [Conjugation Chemistry/Click Chemistry]
• PEG Azides/Alkynes [Conjugation Chemistry/Click Chemistry]
• trans-Cyclooctenes (TCO) [Conjugation Chemistry/Click Chemistry]

Back to Conjugation Chemistry/Click Chemistry. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — the official distributor of TCI Japan in Indonesia — to check availability and lead time directly from Japan.