Good's Buffering Agents

Good's Buffering Agents — encompasses zwitterionic compounds derived from sulfonic acids and substituted amino acids, designed to maintain a stable pH in the physiological range. This class is known as Good's buffers because of their minimal interference with biochemical reactions compared to conventional phosphate buffers.

Good's Buffering Agents are widely used by molecular biology and biochemistry researchers in cell culture, electrophoresis, and enzymatic assays that require pH stability without disrupting protein activity. Compounds such as CAPSO, TAPSO, and Bicine are also used in culture media formulations and buffer solutions for protein chromatography.

Example products in this collection: TCI C0921 1135-40-6 3-Cyclohexylaminopropanesulfonic Acid [Good's buffer component for biological research], TCI C0920 103-47-9 2-Cyclohexylaminoethanesulfonic Acid [Good's buffer component for biological research], TCI T1364 68399-81-5 3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic Acid [Good's buffer component for biological research], TCI H0396 7365-45-9 2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethanesulfonic Acid [Good's buffer component for biological research], TCI B1494 68399-80-4 3-[N,N-Bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic Acid, TCI H0576 16052-06-5 4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic Acid [Good's buffer component for biological research], TCI B1493 6976-37-0 Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane [Good's buffer component for biological research], TCI H0671 68399-77-9 2-Hydroxy-3-morpholinopropanesulfonic Acid.

Match the pKa range of the compound to the desired working pH, and consider solubility and the crystal or powder form for easier weighing and dissolution. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other categories at the same level under Biological Buffers, often used together in a single laboratory workflow:

Back to Biological Buffers. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — to check availability and lead time directly from Japan.

13 products