Collection: MS Derivatization Reagents

MS Derivatization Reagents — includes derivatization reagents such as Girard's Reagent T, DAABD-Cl, and triazolinedione derivatives that react with specific functional groups on the analyte. These condensation, acylation, or addition reactions convert the target compound into a form that is easier to detect and separate by mass spectrometry.

MS Derivatization Reagents are used by proteomics researchers and metabolite analysis practitioners to label amine, carbonyl, or carboxylic acid groups before LC-MS/MS analysis, thereby increasing detection sensitivity and chromatographic separation. Reagents such as 2-Aminobenzamide are used for glycan labeling, while p-Toluenesulfonyl Isocyanate is commonly used for derivatization of hydroxyl groups in quantitative analysis workflows.

Examples of products in this collection: TCI A0262 88-68-6 2-Aminobenzamide, TCI C0205 2921-14-4 Carboxymethoxylamine Hemihydrochloride, TCI B0457 123-46-6 Girard's Reagent T, TCI D0005 605-65-2 Dansyl Chloride (10% in Acetone), TCI A5596 664985-43-7 DAABD-Cl [=4-[2-(Dimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole] [for Proteome Analysis], TCI D0656 605-65-2 Dansyl Chloride, TCI T0998 4083-64-1 p-Toluenesulfonyl Isocyanate, TCI D0727 5787-71-3 Girard's Reagent D.

Selection of a derivatization reagent should consider the suitability of the reactive group for the target analyte, material purity, storage stability, and compatibility of the reaction product with the chromatography or mass spectrometry system being used. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other categories that are parallel under Derivatization Reagents, often used together in one laboratory workflow:

Back to Derivatization Reagents. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — the official TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.

11 products