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TCI

CAS 54-25-1

6-Azauridine TCI A0559

6-Azauridine TCI A0559

Chemical Identity

CAS No.
54-25-1
PubChem
CID 5901·SID 87562154
Formula
C8H11N3O6
Molecular weight
245.19 g/mol
Purity
>99.0%(HPLC)
Reference databases
ChEBI·ChemSpider·ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazine-3,5-dione
SMILES
C1=NN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
InChIKey
WYXSYVWAUAUWLD-SHUUEZRQSA-N
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6-Azauridine is a chemical compound widely used in biochemical and molecular biology experiments. Its structure closely resembles a nucleotide, enabling it to interact with enzymes such as DNA polymerase. This interaction makes it a valuable tool in studying the mechanisms of DNA replication and RNA transcription. In the laboratory, it is commonly used to inhibit DNA synthesis, serving as an essential component in research related to cell growth and cancer processes. Its ability to bind and inhibit DNA enzymes makes it a preferred choice for various biochemical applications.

The chemical properties of 6-Azauridine make it a preferred choice for laboratory use. It exhibits stability under certain conditions but remains highly reactive in reactions involving nucleotides. This reactivity, combined with its ability to effectively bind DNA enzymes, ensures its utility in a range of biotechnological applications. Its solid form and ease of handling further enhance its practicality in laboratory settings. These characteristics make it a reliable and efficient reagent for both research and educational purposes.

In Indonesian laboratories, 6-Azauridine is commonly used in biomedical and pharmacological research. It is an essential component in studies examining the pharmacological effects and mechanisms of drug action. Many research institutions in Indonesia utilize this compound for experimental purposes, including educational experiments at universities. Its versatility and effectiveness make it a popular choice among researchers and educators in the region.

  • Biochemical Research: 6-Azauridine is ideal for studying DNA replication and enzyme inhibition due to its nucleotide-like structure and interaction with DNA polymerase.
  • Cancer Cell Studies: It is used to inhibit DNA synthesis, making it valuable for investigating cell growth and tumor development mechanisms.
  • Pharmacological Investigations: The compound aids in analyzing drug mechanisms by studying its effects on DNA and enzyme activity.
  • Molecular Biology Experiments: Its ability to bind DNA enzymes makes it suitable for experiments involving nucleic acid chemistry and genetic processes.
  • Educational Research: It is commonly used in university laboratories for teaching and demonstrating biochemical and molecular biology concepts.

Brand TCI
CAS number 54-25-1
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Nucleic Acid Chemistry
Pack sizes Available in various quantities as per supplier specifications
Physical form Solid
Storage Store in a cool, dry place away from light and moisture

6-Azauridine should be stored in a cool, dry place, away from light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to air and humidity. As a reactive compound, it should be handled with care in a well-ventilated laboratory environment. Protective gloves and safety goggles are advised during handling to ensure personal safety. Proper disposal procedures should be followed to comply with laboratory safety standards and environmental regulations. Regular monitoring of storage conditions is essential to preserve the integrity and effectiveness of the compound.

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