Dansyl Hydrazine TCI A5552, with CAS number 33008-06-9, is a chemical compound widely used in laboratory settings for conjugation and labeling applications, particularly in High-Performance Liquid Chromatography (HPLC). This reagent plays a crucial role in chemical biology by enabling the attachment of detectable functional groups to target molecules. Its application is essential in analytical chemistry for enhancing the identification and analysis of complex mixtures. In the lab, it is used to chemically bind to various substrates, facilitating precise and sensitive detection methods.
The unique properties of Dansyl Hydrazine make it a preferred choice for researchers. It exhibits chemical stability under specific conditions and reacts efficiently with a range of substrates, including proteins, amino acids, and organic compounds. Its ability to generate strong fluorescence after reaction significantly improves detection sensitivity and accuracy in HPLC applications. This characteristic is particularly valuable in studies requiring high-resolution analysis and reliable identification of molecular components.
In Indonesian laboratories, Dansyl Hydrazine is commonly used in biomedical, pharmacological, and analytical chemistry research. It supports studies that require molecular detection and separation techniques, especially in environments where precision and reliability are critical. Its versatility and effectiveness make it a key reagent in modern chemical research and development.
Advantages (TCI brochure)
- Green-yellow fluorescence from dansyl core, dependent on environment
TCI brochures (PDF)
- Fluorescent Labeling Dyes 2025-11-18 · p. 2
- HPLC Labeling Reagents 2026-03-10 · p. 3
- Reagents for Biological Research 2025-03-11 · p. 4
Related TCI products
- TCI A5573 221263-97-4 NBD-CO-Hz [=4-(N-Hydrazinocarbonylmethyl-N-methylamino)-7-nitro-2,1,3-benzoxadiazole] [for HPLC Labeling]
- TCI A5571 179951-63-4 DBD-CO-Hz [=4-(N,N-Dimethylaminosulfonyl)-7-(N-hydrazinocarbonylmethyl-N-methyl)amino-2,1,3-benzoxadiazole] [for HPLC Labeling]
- TCI A5557 131467-87-3 NBD-H (=4-Hydrazino-7-nitro-2,1,3-benzoxadiazole Hydrazine) [for HPLC Labeling]
- TCI D0656 605-65-2 Dansyl Chloride
- TCI A5595 98358-90-8 DBD-F [=4-(N,N-Dimethylaminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole] [for HPLC Labeling]
- TCI A5593 29270-56-2 NBD-F (=4-Fluoro-7-nitro-2,1,3-benzoxadiazole) [for HPLC Labeling]
- High-Performance Liquid Chromatography (HPLC) benefits from Dansyl Hydrazine as it enables fluorescent labeling of compounds, enhancing detection sensitivity and specificity in complex mixtures.
- Bioconjugation applications utilize this reagent to attach fluorescent tags to biomolecules, aiding in tracking and analysis of molecular interactions in biological systems.
- Protein labeling in biochemical research relies on Dansyl Hydrazine to mark specific amino acid residues, allowing for detailed structural and functional studies.
- Analytical chemistry experiments use this compound to improve the identification of organic compounds through enhanced fluorescence, supporting accurate quantification and separation.
- Drug development processes incorporate Dansyl Hydrazine for labeling and tracking of pharmaceutical compounds during early-stage research and formulation testing.
From the TCI brochure
- Can be labeled to carbonyl groups by hydrazone bond formation
| Brand | TCI |
|---|---|
| CAS number | 33008-06-9 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Chemical Biology > Conjugation Chemistry/Click Chemistry |
| Pack sizes | — |
| Physical form | — |
| Storage | Store in a cool, dry place away from light |
Data from the TCI brochure
| λex,max | ca. 335 nm |
|---|---|
| λem,max | ca. 460 nm |
Source: TCI brochure LL039 (2025-11-18)
Dansyl Hydrazine should be stored in a cool, dry place, away from direct light and sources of heat. It is recommended to keep the material in a sealed container to prevent moisture absorption and contamination. Proper ventilation is essential when handling the compound to minimize exposure to vapors. Laboratory personnel should wear appropriate personal protective equipment, such as gloves and safety goggles, when working with this reagent. It is important to maintain a clean and organized workspace to reduce the risk of accidental spills or cross-contamination. Always follow standard safety protocols to ensure safe handling and storage of chemical substances in the laboratory environment.
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