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TCI

CAS 33008-06-9

Dansyl Hydrazine [for HPLC Labeling] TCI A5552

Dansyl Hydrazine [for HPLC Labeling] TCI A5552

Chemical Identity

CAS No.
33008-06-9
PubChem
CID 94442·SID 87563170
Formula
C12H15N3O2S
Molecular weight
265.33 g/mol
Purity
>97.0%(T)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
5-(dimethylamino)naphthalene-1-sulfonohydrazide
SMILES
CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)NN
InChIKey
KPQYDVAFRDWIBW-UHFFFAOYSA-N
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Dansyl Hydrazine TCI A5552, with CAS number 33008-06-9, is a chemical compound widely used in laboratory settings for conjugation and labeling applications, particularly in High-Performance Liquid Chromatography (HPLC). This reagent plays a crucial role in chemical biology by enabling the attachment of detectable functional groups to target molecules. Its application is essential in analytical chemistry for enhancing the identification and analysis of complex mixtures. In the lab, it is used to chemically bind to various substrates, facilitating precise and sensitive detection methods.

The unique properties of Dansyl Hydrazine make it a preferred choice for researchers. It exhibits chemical stability under specific conditions and reacts efficiently with a range of substrates, including proteins, amino acids, and organic compounds. Its ability to generate strong fluorescence after reaction significantly improves detection sensitivity and accuracy in HPLC applications. This characteristic is particularly valuable in studies requiring high-resolution analysis and reliable identification of molecular components.

In Indonesian laboratories, Dansyl Hydrazine is commonly used in biomedical, pharmacological, and analytical chemistry research. It supports studies that require molecular detection and separation techniques, especially in environments where precision and reliability are critical. Its versatility and effectiveness make it a key reagent in modern chemical research and development.

Advantages (TCI brochure)

  • Green-yellow fluorescence from dansyl core, dependent on environment

TCI brochures (PDF)

  • High-Performance Liquid Chromatography (HPLC) benefits from Dansyl Hydrazine as it enables fluorescent labeling of compounds, enhancing detection sensitivity and specificity in complex mixtures.
  • Bioconjugation applications utilize this reagent to attach fluorescent tags to biomolecules, aiding in tracking and analysis of molecular interactions in biological systems.
  • Protein labeling in biochemical research relies on Dansyl Hydrazine to mark specific amino acid residues, allowing for detailed structural and functional studies.
  • Analytical chemistry experiments use this compound to improve the identification of organic compounds through enhanced fluorescence, supporting accurate quantification and separation.
  • Drug development processes incorporate Dansyl Hydrazine for labeling and tracking of pharmaceutical compounds during early-stage research and formulation testing.

From the TCI brochure

  • Can be labeled to carbonyl groups by hydrazone bond formation

Brand TCI
CAS number 33008-06-9
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Conjugation Chemistry/Click Chemistry
Pack sizes —
Physical form —
Storage Store in a cool, dry place away from light

Data from the TCI brochure

λex,maxca. 335 nm
λem,maxca. 460 nm

Source: TCI brochure LL039 (2025-11-18)

Dansyl Hydrazine should be stored in a cool, dry place, away from direct light and sources of heat. It is recommended to keep the material in a sealed container to prevent moisture absorption and contamination. Proper ventilation is essential when handling the compound to minimize exposure to vapors. Laboratory personnel should wear appropriate personal protective equipment, such as gloves and safety goggles, when working with this reagent. It is important to maintain a clean and organized workspace to reduce the risk of accidental spills or cross-contamination. Always follow standard safety protocols to ensure safe handling and storage of chemical substances in the laboratory environment.

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