(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid is a specialized chemical compound widely used in peptide chemistry and molecular synthesis. This compound serves as a key building block in the development of bioactive molecules and pharmaceuticals. Its unique structure, featuring a pyrrolidine ring with a fluorine atom and a tert-butoxycarbonyl (Boc) protecting group, makes it highly versatile for chemical modifications. In laboratory settings, it is essential for researchers aiming to design and synthesize complex peptides and drug candidates.
The compound is valued for its chemical stability and compatibility with various synthetic methods. The presence of the Boc group allows for controlled protection of amino groups, which is critical in multi-step peptide synthesis. Its fluorinated side chain also contributes to its reactivity and specificity in chemical reactions. These properties make it a preferred choice for chemists working in chemical biology and medicinal chemistry. The compound’s ability to undergo selective deprotection and modification ensures its utility in advanced research applications.
In Indonesian laboratories, this compound is commonly used in academic and industrial research settings. It supports studies in drug discovery, peptide engineering, and bioactive molecule development. Researchers in pharmaceutical and biotechnology sectors rely on its structural versatility to create novel compounds with specific biological activities. Its role in synthetic chemistry makes it an essential tool for advancing scientific innovation in Indonesia.
TCI brochures (PDF)
- Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 13
- Fluorination Reagents, Fluorinated Building Blocks 2026-03-18 · p. 46
Related TCI products
- TCI B3178 203866-13-1 (2S,4S)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
- TCI B3304 41153-30-4 N-(tert-Butoxycarbonyl)-4-fluoro-L-phenylalanine
- TCI B5350 68856-96-2 N-(tert-Butoxycarbonyl)-4-methoxy-D-phenylalanine
- TCI B5322 159622-10-3 (1R,2S)-1-[(tert-Butoxycarbonyl)amino]-2-vinylcyclopropanecarboxylic Acid
- TCI B5011 85466-66-6 N-(tert-Butoxycarbonyl)-N-methyl-D-phenylalanine
- TCI B4369 114873-07-3 N-(tert-Butoxycarbonyl)-4-trifluoromethyl-L-phenylalanine
- Peptide Synthesis: The compound is ideal for constructing complex peptides due to its pyrrolidine core and Boc protecting group, enabling controlled amino acid coupling.
- Drug Development: Its fluorinated structure enhances molecular specificity, making it valuable in the design of bioactive pharmaceutical compounds.
- Molecular Modification Studies: The compound’s reactivity allows for targeted chemical modifications, supporting research into functionalized molecules.
- Bioactive Compound Research: The fluorine atom contributes to the compound’s biological activity, aiding in the development of therapeutic agents.
- Academic Research: Used in educational and exploratory studies to teach and develop synthetic methodologies in chemical biology.
| Brand | TCI |
|---|---|
| CAS number | 203866-14-2 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Chemical Biology > Peptide Chemistry |
| Pack sizes | Available in standard laboratory quantities |
| Physical form | Solid powder |
| Storage | Store in a cool, dry place away from moisture and light |
This compound should be stored in a cool, dry environment to maintain its chemical integrity and stability. It is recommended to keep it in a tightly sealed container to prevent exposure to moisture and air. Due to its chemical nature, it should be handled in a well-ventilated laboratory setting to minimize inhalation risks. Avoid direct contact with skin and eyes, and use appropriate personal protective equipment such as gloves and safety goggles. The compound is not flammable but should be stored away from incompatible substances. Regular inspection of storage conditions ensures optimal preservation and safety in laboratory environments.
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Product Categories
- Chemical BiologyPeptide ChemistryAmino Acid Derivatives [Peptide Chemistry]
- Chemical BiologyPeptide ChemistryUnnatural Amino Acid Derivatives
- Pharmaceutical Development and Drug Discovery Research ReagentsPeptide ChemistryAmino Acid Derivatives [Peptide Chemistry]
- Pharmaceutical Development and Drug Discovery Research ReagentsPeptide ChemistryUnnatural Amino Acid Derivatives




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