(2S,4S)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid is a specialized chemical compound widely used in laboratory settings for its unique structural and functional properties. This compound plays a vital role in chemical biology and peptide chemistry, particularly in the synthesis of bioactive molecules. Its application spans across organic and biochemical research, where precise control over molecular reactivity and stability is essential. Due to its specific functional groups, it is frequently employed in the development of peptides and their analogs, contributing to the advancement of pharmaceutical and biotechnological research.
The compound's preference in laboratory settings is due to its favorable solubility in organic solvents such as ethyl acetate and its strong attachment to the tert-butoxycarbonyl (Boc) group. These characteristics allow for controlled chemical reactions, including coupling and deprotection processes, which are fundamental in peptide synthesis. The presence of the fluorine atom further enhances its electronic and reactive properties, making it a valuable tool in the design of compounds with specific biological activities. Its stability and reactivity make it a reliable choice for researchers aiming to produce complex molecular structures.
In Indonesian laboratories, this compound is commonly used in academic and industrial research settings. It is a key component in the development of bioactive compounds, particularly in pharmaceutical and biochemical studies. Its role in peptide synthesis and its ability to participate in controlled chemical reactions make it an essential reagent for scientists working on drug discovery and molecular design. Its application is widespread in both research and development laboratories across Indonesia.
TCI brochures (PDF)
- Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 13
- Fluorination Reagents, Fluorinated Building Blocks 2026-03-18 · p. 46
Related TCI products
- TCI B3177 203866-14-2 (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
- TCI B3304 41153-30-4 N-(tert-Butoxycarbonyl)-4-fluoro-L-phenylalanine
- TCI B5350 68856-96-2 N-(tert-Butoxycarbonyl)-4-methoxy-D-phenylalanine
- TCI B5322 159622-10-3 (1R,2S)-1-[(tert-Butoxycarbonyl)amino]-2-vinylcyclopropanecarboxylic Acid
- TCI B5011 85466-66-6 N-(tert-Butoxycarbonyl)-N-methyl-D-phenylalanine
- TCI B4369 114873-07-3 N-(tert-Butoxycarbonyl)-4-trifluoromethyl-L-phenylalanine
- Peptide Synthesis: This compound is ideal for peptide synthesis due to its Boc protecting group, allowing controlled deprotection and coupling reactions in solid-phase peptide synthesis.
- Bioactive Compound Development: Its fluorinated structure provides unique electronic properties, making it suitable for designing compounds with specific biological activities.
- Organic Chemistry Research: The compound's solubility in organic solvents and reactivity make it a valuable reagent in synthetic organic chemistry experiments.
- Molecular Design Studies: Its structural versatility supports research into molecular design, particularly in the development of drug candidates with tailored pharmacological profiles.
- Biotechnology Applications: The compound is used in biotechnology research to create modified peptides and analogs for therapeutic and diagnostic purposes.
| Brand | TCI |
|---|---|
| CAS number | 203866-13-1 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Chemical Biology > Peptide Chemistry |
| Pack sizes | Available in various quantities as per supplier specifications |
| Physical form | Solid powder |
| Storage | Store in a cool, dry place away from moisture and direct sunlight |
This compound should be stored in a cool, dry environment, away from moisture and direct sunlight to maintain its chemical integrity. It is recommended to use airtight containers made of glass or high-density polyethylene to prevent contamination and degradation. Due to its reactivity, it should be handled in a well-ventilated laboratory area, preferably under a fume hood, to minimize exposure. Proper personal protective equipment, including gloves and safety goggles, should be worn when handling the compound. It is important to ensure that the storage area is secure and accessible only to authorized personnel to prevent accidental exposure or misuse.
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Product Categories
- Chemical BiologyPeptide ChemistryAmino Acid Derivatives [Peptide Chemistry]
- Chemical BiologyPeptide ChemistryUnnatural Amino Acid Derivatives
- Pharmaceutical Development and Drug Discovery Research ReagentsPeptide ChemistryAmino Acid Derivatives [Peptide Chemistry]
- Pharmaceutical Development and Drug Discovery Research ReagentsPeptide ChemistryUnnatural Amino Acid Derivatives




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