Bis(NHS)PEG5 TCI B3728

Chemical Identity

CAS No.: 756526-03-1
PubChem: CID 51340935·SID 172089011
Formula: C22H32N2O13
Molecular weight: 532.5 g/mol

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O
InChIKey: FTYUGLBWKRXQBD-UHFFFAOYSA-N

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Bis(NHS)PEG5 is a chemical compound widely used in the field of PEGylation, a process that involves the modification of biological molecules with polyethylene glycol (PEG). This material plays a crucial role in laboratory settings by enhancing the stability, solubility, and longevity of therapeutic agents within the body. As a key reagent in chemical biology, it enables researchers to develop more effective and safer drug formulations. Its application spans various areas of biomedical research, including the development of vaccines, biopharmaceuticals, and targeted therapies.

The compound is known for its stable chemical structure and high reactivity, which allows it to efficiently conjugate with amino or carboxyl groups on target molecules. These properties make it a preferred choice for molecular conjugation processes. Additionally, Bis(NHS)PEG5 is non-toxic and compatible with a wide range of reaction conditions, ensuring consistent and predictable results. Its reliability and versatility make it an essential tool in modern laboratory research.

In Indonesian laboratories, Bis(NHS)PEG5 is commonly used in scientific research, particularly in biomedical and pharmaceutical fields. Researchers rely on this compound to advance drug development and improve the efficacy of therapeutic agents. Its consistent performance and ease of use make it a valuable resource for both academic and industrial research settings.

TCI brochures (PDF)

Cross-linkers 2026-04-14 · p. 1
Drug Delivery System (DDS) Research Reagents 2025-01-29 · p. 3
Bioconjugation Reagents 2026-07-07 · p. 7
Reagents for Biological Research 2025-03-11 · p. 28

Related TCI products

PEGylation of therapeutic proteins for enhanced drug delivery and reduced immunogenicity.
Development of biopharmaceuticals with improved stability and bioavailability.
Targeted drug conjugation for cancer therapy and precision medicine applications.
Research into vaccine formulation and immunological responses in biomedicine.
Modification of biomolecules for diagnostic and therapeutic purposes in pharmaceutical studies.

Brand	TCI
CAS number	756526-03-1
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > PEGylation
Pack sizes	Available in various sizes as per supplier specifications
Physical form	Solid or powder, depending on formulation
Storage	Store in a cool, dry place away from direct sunlight

Bis(NHS)PEG5 should be stored in a cool, dry environment to maintain its chemical stability and reactivity. It is recommended to keep the compound in a sealed container to prevent moisture absorption and contamination. Suitable containers include glass or high-density polyethylene (HDPE) bottles, which provide protection against chemical degradation. In laboratory settings, it is important to handle the compound with appropriate personal protective equipment (PPE) such as gloves and safety goggles. Avoid exposure to extreme temperatures or direct sunlight to ensure product integrity. Regular monitoring of storage conditions is advised to maintain optimal performance and safety during use.

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