• 1-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic Acid (CAS 115951-16-1) - TCI B6437 - AMI Scientific
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TCI

CAS 115951-16-1

1-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic Acid TCI B6437

1-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic Acid TCI B6437
Rp 1.829.100,00
Rp 1.829.100,00
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TCI B6437 1-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic Acid (CAS 115951-16-1) is a Boc-protected cyclic amino acid in which the amino and carboxyl groups share a quaternary carbon. Its rigid cyclohexane framework makes it valuable for designing conformationally constrained peptides and peptide analogues. The pre-installed Boc group saves a protection step and can be removed under well-established acidic conditions. Store the solid tightly sealed in a cool, dry place away from strong acids, and refer to the manufacturer's safety data sheet before handling.

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  • Badland et al. (2010). An improved synthesis of (1R,3S)-3-[(tert-butoxycarbonyl)amino]cyclohexanecarboxylic acid. Tetrahedron: Asymmetry doi:10.1016/j.tetasy.2010.04.049
  • Kadyrov et al. (2021). Convenient Synthesis of (R)-3-[(tert-Butoxycarbonyl)amino]piperidine and (R)-3-[(tert-Butoxycarbonyl)amino]azepane. Synthesis doi:10.1055/a-1526-7657
  • (2012). Discussion Addendum For: Efficient Asymmetric Synthesis of N-tert-Butoxycarbonyl a-Amino Acids using 4-tert-Butoxycarbonyl-5,6-Diphenylmorpholin-2-one:. Organic Syntheses doi:10.15227/orgsyn.089.0394

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