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Description
2-Bromo-N-phenylacetamide (TCI B6588, CAS 5326-87-4) is an α-bromoacetamide bearing an N-phenyl group, valued for the high reactivity of its alpha bromine. It readily undergoes substitution with amines, thiols, phenols, and thiourea, making it a versatile alkylating building block. A common use is the construction of thiazole rings through condensation with thiourea or thioamides, alongside the preparation of substituted glycinamide derivatives. Because α-halocarbonyl compounds are typically irritating and lachrymatory, all handling should take place in a fume hood with appropriate personal protective equipment.
