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Description
TCI C0229 4-Nitrobenzyl Chloride (CAS 100-14-1) is a non-heterocyclic building block widely used in organic synthesis laboratories. Its activated benzylic chloride readily alkylates oxygen, nitrogen, and sulfur nucleophiles, while the para-nitro group provides a strong ultraviolet chromophore. Researchers commonly apply it to derivatize carboxylic acids for HPLC detection and to install a removable protecting group during multistep synthesis. AMI Scientific supplies this TCI reagent in 25 g and 250 g packs for academic, pharmaceutical, and industrial research use.
Scientific References
JENSEN et al. (1998). ChemInform Abstract: Solvent Effects on the Reduction Mechanism of 9‐Chloroanthracene, 3‐Nitrobenzyl Chloride, and 3‐Chloroacetophenone.. ChemInformdoi:10.1002/chin.199851067
Giuglio‐Tonolo et al. (2003). Original Reaction of p‐Nitrobenzyl Chloride with Aldehydes Using Tetrakis(dimethylamino)ethylene (TDAE).. ChemInformdoi:10.1002/chin.200347095
BARELMANN et al. (1991). ChemInform Abstract: Simultaneous Electrochemical Electron Paramagnetic Resonance Investigation of the Reduction of p‐Nitrobenzyl Chloride.. ChemInformdoi:10.1002/chin.199103049
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
