TCI
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Description
TCI C0709 3-Nitrobenzyl Chloride, CAS 619-23-8, is a crystalline bifunctional aromatic reagent bearing both a reactive chloromethyl group and a meta-nitro substituent. The chloromethyl group readily benzylates amines, alcohols, thiols, and carbanions, while the nitro group can be reduced to an aniline for further elaboration. AMI Scientific offers this TCI building block in 5 g and 25 g packs for pharmaceutical intermediate, dye, and materials research. It is corrosive and a strong lachrymator, so weigh and transfer it only in a fume hood with full personal protective equipment and keep it dry and tightly sealed.
Scientific References
- JENSEN et al. (1998). ChemInform Abstract: Solvent Effects on the Reduction Mechanism of 9‐Chloroanthracene, 3‐Nitrobenzyl Chloride, and 3‐Chloroacetophenone.. ChemInform doi:10.1002/chin.199851067
- BARELMANN et al. (1991). ChemInform Abstract: Simultaneous Electrochemical Electron Paramagnetic Resonance Investigation of the Reduction of p‐Nitrobenzyl Chloride.. ChemInform doi:10.1002/chin.199103049
- Giuglio‐Tonolo et al. (2003). Original Reaction of p‐Nitrobenzyl Chloride with Aldehydes Using Tetrakis(dimethylamino)ethylene (TDAE).. ChemInform doi:10.1002/chin.200347095
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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