4-Nitrobenzyl Chloroformate (TCI C1077, CAS 4457-32-3) is a widely used reagent for installing the p-nitrobenzyloxycarbonyl (pNZ) protecting group on amines in peptide chemistry. Because the pNZ group is removed under reductive conditions, it provides valuable orthogonality against acid- and base-labile protecting groups. AMI Scientific supplies this TCI reagent in a 25 g pack size suited to research and development laboratories. As a moisture-sensitive and corrosive chloroformate, it should be handled in a fume hood following the official TCI Safety Data Sheet.
TCI brochures (PDF)
- Condensing Agents 2025-11-18 · p. 5
Related TCI products
- TCI C1400 7693-46-1 4-Nitrophenyl Chloroformate
- TCI C0178 543-27-1 Isobutyl Chloroformate
- TCI B0249 6066-82-6 N-Hydroxysuccinimide [Coupling Reagent for Peptide]
- TCI T0681 658-78-6 4-Nitrophenyl Trifluoroacetate
- TCI P0919 771-61-9 Pentafluorophenol
- TCI M3572 214754-50-4 2-Hydroxy-5-methoxyisoindoline-1,3-dione
—
| Brand | — |
|---|---|
| CAS number | — |
| Molecular formula | — |
| Purity | — |
| Category | — |
| Pack sizes | — |
| Physical form | — |
| Storage | — |
—
—



![6066-82-6 N-Hydroxysuccinimide [Coupling Reagent for Peptide] - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510B0249.jpg?v=1767085300&width=533)




