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Description
TCI C1495 (S)-(+)-Camptothecin (CAS 7689-03-4) is a pentacyclic quinoline alkaloid and a well-characterised topoisomerase I inhibitor. It is catalogued as a research reagent for pharmaceutical development, particularly for antibody-drug conjugate preparation, where its scaffold underpins an important class of payloads. Laboratories also use it as a positive control in cytotoxicity assays and as a starting material for analog synthesis. Supplied in 100 mg and 1 g packs; treat as a cytotoxic compound and follow the Safety Data Sheet and institutional handling procedures.
Scientific References
A et al. (2016). ANNUAL VARIATION IN CAMPTOTHECIN AND 9-METHOXY CAMPTOTHECIN ACCUMULATION AND ITS DETERMINATION IN DIFFERENT PARTS OF NOTHAPODYTES NIMMONIANA BY HPLC ANALYSIS. Bulletin of Pharmaceutical Researchdoi:10.21276/bpr.2016.6.1.3
(2002). Crystal Form of A Camptothecin Derivative. Journal of Korean Pharmaceutical Sciencesdoi:10.4333/kps.2002.32.2.081
(2018). Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5. Cancer Genomics & Proteomicsdoi:10.21873/cgp.20068
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
