TCI C1495 (S)-(+)-Camptothecin (CAS 7689-03-4) is a pentacyclic quinoline alkaloid and a well-characterised topoisomerase I inhibitor. It is catalogued as a research reagent for pharmaceutical development, particularly for antibody-drug conjugate preparation, where its scaffold underpins an important class of payloads. Laboratories also use it as a positive control in cytotoxicity assays and as a starting material for analog synthesis. Supplied in 100 mg and 1 g packs; treat as a cytotoxic compound and follow the Safety Data Sheet and institutional handling procedures.
TCI brochures (PDF)
- Crude Medicine Ingredients for Cancer Research 2025-02-17 · p. 1
- Traditional Medicine/Crude Medicine Research Reagents 2024-09-11 · p. 1
- Alkaloids 2025-10-10 · p. 5
- Cancer Research Reagents 2025-04-01 · p. 2
- Plant Research Reagents 2026-02-24 · p. 8
- Phytochemicals 2025-12-17 · p. 3
From the TCI brochure
- Antitumor agent; acts on the DNA composition of tumor cells and their activities (review cited, ref 6)
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- A et al. (2016). ANNUAL VARIATION IN CAMPTOTHECIN AND 9-METHOXY CAMPTOTHECIN ACCUMULATION AND ITS DETERMINATION IN DIFFERENT PARTS OF NOTHAPODYTES NIMMONIANA BY HPLC ANALYSIS. Bulletin of Pharmaceutical Research doi:10.21276/bpr.2016.6.1.3
- (2002). Crystal Form of A Camptothecin Derivative. Journal of Korean Pharmaceutical Sciences doi:10.4333/kps.2002.32.2.081
- (2018). Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5. Cancer Genomics & Proteomics doi:10.21873/cgp.20068
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
Product Categories
- Biochemicals and ReagentsAlkaloidsQuinoline Alkaloids
- Biochemicals and ReagentsAntibody-Drug Conjugates (ADC) Preparation Research ReagentsPayload (Drug) Candidates [ADC Preparation Research Reagents]
- Biochemicals and ReagentsCrude Medicine Ingredients for Research and Experimental Use
- Biochemicals and ReagentsEnzymes, Enzyme Inhibitors, Enzyme SubstratesEnzyme Inhibitors [Biochemicals and Reagents]
- Biochemicals and ReagentsPharmaceutical Research Reagents (for Experimental Use)Antitumor Research Reagents (for Experimental Use)
- Cell BiologyApoptosisApoptosis Inducers
- Cell BiologyCancer ResearchAntitumor Agents for Research
- Cell BiologyNutrition ResearchPhytochemicals
- Pharmaceutical Development and Drug Discovery ResearchAntibody-Drug Conjugates (ADC) Preparation Research ReagentsPayload (Drug) Candidates [ADC Preparation Research Reagents]
- Pharmaceutical Development and Drug Discovery ResearchPharmaceutical Research Reagents (for Experimental Use)Antitumor Research Reagents (for Experimental Use)
- Pharmaceutical Development and Drug Discovery ResearchCrude Medicine Ingredients for Research and Experimental Use
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