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TCI

CAS 136572-09-3

Irinotecan Hydrochloride Trihydrate TCI I0714

Irinotecan Hydrochloride Trihydrate TCI I0714

Chemical Identity

CAS No.
136572-09-3
PubChem
CID 74990·SID 87560270
Formula
C33H39ClN4O6
Molecular weight
623.1 g/mol
Purity
>98.0%(HPLC)(T)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate;hydrochloride
SMILES
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
InChIKey
GURKHSYORGJETM-WAQYZQTGSA-N
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Irinotecan Hydrochloride Trihydrate is a chemical compound widely used in life sciences research, particularly in biochemistry and pharmaceutical studies. It plays a crucial role in investigating anti-cancer activity and the mechanisms of drug action. As a synthetic alkaloid, it is commonly utilized in laboratories to explore biological effects and its ability to inhibit cancer cell growth. This compound is essential for researchers aiming to understand the molecular pathways involved in tumor suppression and drug development. Its presence in research settings supports both fundamental and applied studies in oncology and medicinal chemistry.

The compound's chemical stability and solubility in organic solvents make it a preferred choice for various experimental applications. These properties ensure consistent performance in different laboratory procedures, including synthesis reactions, enzymatic activity assays, and quantitative analysis. Its high purity and reproducible quality further enhance its reliability as a reagent in scientific investigations. These characteristics contribute to its widespread use in both academic and industrial research environments, where precision and consistency are paramount.

In Indonesian laboratories, Irinotecan Hydrochloride Trihydrate is commonly used in clinical and basic research applications. It is particularly relevant for studies on cancer therapy and the development of new pharmaceuticals. Researchers in educational and research institutions frequently employ this compound for experiments requiring a reliable and well-characterized reagent. Its availability and performance make it a valuable tool in advancing scientific knowledge and innovation in the field of life sciences.

  • Anti-Cancer Drug Development: This compound is used to evaluate the efficacy of cancer treatments and to study the molecular mechanisms of drug action in tumor cells.
  • Enzymatic Activity Assays: Its solubility in organic solvents makes it suitable for enzyme inhibition studies and biochemical pathway investigations.
  • Quantitative Analysis: The compound's stability and purity allow it to be used in analytical techniques such as HPLC and mass spectrometry for accurate quantification.
  • Synthetic Chemistry: It serves as a key reagent in the synthesis of complex organic molecules and pharmaceutical compounds.
  • Pharmacological Research: It is employed to study the pharmacokinetics and pharmacodynamics of anti-cancer agents in preclinical models.

Brand TCI
CAS number 136572-09-3
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Alkaloids
Pack sizes Available in various quantities as per standard laboratory requirements
Physical form Solid
Storage Store in a cool, dry place away from light and moisture

Irinotecan Hydrochloride Trihydrate should be stored in a cool, dry environment, away from direct light and moisture. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its chemical properties, it is essential to handle the compound with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Avoid contact with skin and eyes, and ensure proper ventilation when working with the compound. It should not be disposed of in the environment without following appropriate waste disposal guidelines. Regular monitoring of storage conditions helps maintain the compound's stability and effectiveness for research applications.

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