Methanesulfonic Acid TCI M0093

Chemical Identity

CAS No.: 75-75-2
PubChem: CID 6395·SID 87572203
Formula: CH4O3S
Molecular weight: 96.11 g/mol
Purity: >99.0%(T)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: methanesulfonic acid
SMILES: CS(=O)(=O)O
InChIKey: AFVFQIVMOAPDHO-UHFFFAOYSA-N

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Methanesulfonic Acid (MSA), with the CAS number 75-75-2, is a versatile chemical compound widely used in laboratory settings, particularly in organic synthesis. As a strong acid, it serves as a solvent, catalyst, or reactant in various chemical reactions. Its ability to generate stable sulfonate ions makes it highly effective in reactions requiring acidic conditions. MSA is valued for its chemical stability and solubility in both organic solvents and water, making it a reliable choice for a wide range of applications.

One of the key reasons MSA is preferred in laboratories is its excellent solubility and stability under various conditions. It has a high boiling point and good electrical conductivity, which are advantageous in specialized chemical processes. Additionally, its neutral or acidic nature allows it to be used in reactions where pH control is critical. These properties make it a go-to reagent for researchers seeking reliable and consistent results.

In Indonesian laboratories, Methanesulfonic Acid is commonly used in pharmaceutical, organic chemistry, and analytical applications. Its availability and reliability make it a preferred choice for researchers and scientists working on drug development, compound synthesis, and chemical analysis. The compound’s broad utility and stable performance contribute to its popularity in both academic and industrial research settings.

TCI brochures (PDF)

Sulfonimidoylation Reagent TrNSO 2023-01-30 · p. 1
Phosphine Ligand for the Synthesis of Sterically Hindered Biaryls HFTPhos 2026-06-18 · p. 2
Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 38

Related TCI products

Organic synthesis where MSA acts as a catalyst or solvent due to its acidic properties and solubility in various media.
Pharmaceutical research for the synthesis of active pharmaceutical ingredients requiring controlled acidic conditions.
Analytical chemistry applications where MSA is used to adjust pH or as a reagent in titration processes.
Industrial chemical processes that require a stable, non-corrosive acid with good solubility characteristics.
Environmental testing where MSA is used to prepare samples for analysis or as a reagent in specific chemical reactions.

Brand	TCI
CAS number	75-75-2
Molecular formula	—
Purity	—
Category	Chemistry > Synthetic Reagents > Acids, Bases [Synthetic Reagents]
Pack sizes	Available in various sizes as per supplier specifications
Physical form	Liquid
Storage	Store in a cool, dry place away from incompatible materials

Methanesulfonic Acid should be stored in a cool, dry place, away from direct sunlight and incompatible substances such as strong bases or oxidizing agents. It is recommended to use suitable containers made of materials resistant to acid corrosion, such as glass or high-density polyethylene. In laboratory settings, proper personal protective equipment, including gloves, goggles, and a lab coat, should always be worn when handling this compound. Due to its strong acidic nature, it is important to avoid skin contact and inhalation of vapors. The substance should be kept in a well-ventilated area to minimize exposure risks. Always follow standard safety protocols for handling strong acids to ensure a safe working environment.

References cited in the TCI brochure

Gia L. Hoang. Enantioselective Desymmetrization via Carbonyl-Directed Catalytic Asymmetric Hydroboration and Suzuki–Miyaura Cross-Coupling Organic Letters, 2015. doi:10.1021/ol503764d
Svitlana O. Sotnik. Third Generation Buchwald Precatalysts with XPhos and RuPhos: Multigram Scale Synthesis, Solvent-Dependent Isomerization of XPhos Pd G3 and Quality Control by 1H- and 31P-NMR Spectroscopy Molecules, 2021. doi:10.3390/molecules26123507