TCI M2273 Mebendazole is a benzimidazole carbamate compound widely recognized as an anthelmintic agent, meaning an active substance that works against parasitic worms. In the laboratory context, this material is supplied as a research reagent and reference substance, not as a finished pharmaceutical preparation. Researchers use it to study the mechanism of action of the benzimidazole class, to test activity against model organisms, and as a reference compound in the development and validation of analytical methods. Its presence on the laboratory shelf makes it easier for parasitology, pharmacology, and analytical chemistry research groups to obtain a material with a clear and documented identity.
The principal characteristic that makes mebendazole scientifically interesting is its ability to interact with tubulin and disrupt microtubule formation, which makes it a useful tool for examining cytoskeletal dynamics. From a physicochemical standpoint, the compound is practically insoluble in water and only limitedly soluble in most common organic solvents, so researchers normally prepare a stock solution in DMSO or another suitable solvent before dilution. This property demands attention at the working solution preparation stage, since incomplete dissolution can affect the accuracy of concentrations used in an assay.
In Indonesian laboratories, this material is typically used by university research groups, parasitology and pharmacology units, and analytical laboratories that require a reference compound with a documented identity. Supply through AMI Scientific as a distributor of laboratory materials allows research teams to obtain TCI-branded reagents with consistent catalogue identification. The compound is handled as a research reagent, with use limited to research, method development, and analytical testing purposes.
TCI brochures (PDF)
- Antimicrobials and Antitumor Agents for Research and Experimental Use 2025-04-24 · p. 11
- Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 11
- Anthelmintic mechanism studies: the compound serves as the representative benzimidazole for investigating how this drug class acts against parasitic worms under controlled laboratory conditions.
- Activity testing against model organisms: researchers apply it to model systems to observe biological responses, making it suitable for comparative screening work in parasitology research programmes.
- Analytical method development and validation: it functions as a reference compound with documented identity, which is essential when establishing accuracy and specificity of a new analytical procedure.
- Cytoskeletal dynamics research: because it interacts with tubulin and disrupts microtubule formation, it is a useful chemical tool for studying cytoskeleton behaviour in cells.
- Pharmacology teaching and research reference: the material provides a clearly identified benzimidazole standard for pharmacology groups requiring a documented compound for comparative and reference purposes.
| Brand | TCI |
|---|---|
| CAS number | 31431-39-7 |
| Molecular formula | — |
| Purity | — |
| Category | Life Science > Biochemicals and Reagents > Antibiotics |
| Pack sizes | available in the packaging options listed by the manufacturer for this catalogue item |
| Physical form | — |
| Storage | store according to the conditions stated on the manufacturer label and safety data sheet |
- Catalogue code: M2273
Store the container tightly closed in a cool, dry place away from direct sunlight, following the storage conditions stated on the manufacturer label and safety data sheet. Keep the material in its original container or in a tightly sealed, chemically compatible container that is clearly labelled with the compound name, CAS number, and preparation date for any stock solution. Because the compound is practically insoluble in water and only limitedly soluble in common organic solvents, stock solutions are usually prepared in DMSO or another suitable solvent and should be labelled with their concentration. Handle the material as a research reagent using standard laboratory precautions: wear a laboratory coat, gloves, and eye protection, weigh the powder in a well-ventilated area or fume hood to avoid inhaling dust, and avoid direct contact with skin and eyes. Dispose of residues and contaminated materials in accordance with applicable laboratory waste procedures.
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Product Categories
- Biochemicals and ReagentsAntibioticsAntibiotics (by Application)
- Biochemicals and ReagentsPharmaceutical Research Reagents (for Experimental Use)Antiparasitic Ingredients, Antiprotozoal Ingredients, Antihelminthic Ingredients (for Research and Experimental Use)
- Biochemicals and Reagents
- MicrobiologyAntibioticsAntibiotics (by Application)
- Pharmaceutical Development and Drug Discovery ResearchPharmaceutical Research Reagents (for Experimental Use)Antiparasitic Ingredients, Antiprotozoal Ingredients, Antihelminthic Ingredients (for Research and Experimental Use)
- Pharmaceutical Development and Drug Discovery ResearchAntibioticsAntibiotics (by Application)
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